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Antikörper
Artikel-Nr:
(USBIA4159-04D)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A4159-04D
Lokale Artikelnummer::
USBIA4159-04D
Beschreibung:
Anti-ATXN1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-7715R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7715R-HRP
Lokale Artikelnummer::
BOSSBS-7715R-HRP
Beschreibung:
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.Tissue specificity: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.
VE:
1 * 100 µl
Artikel-Nr:
(USBIP9103-20A3BIOT)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9103-20A3BIOT
Lokale Artikelnummer::
USBIP9103-20A3BIOT
Beschreibung:
Anti-PRKCE Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(USBI133884)
Lieferant:
US Biological
Hersteller-Artikelnummer::
133884
Lokale Artikelnummer::
USBI133884
Beschreibung:
Anti-SSX2IP Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBI041682-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041682-FITC
Lokale Artikelnummer::
USBI041682-FITC
Beschreibung:
Anti-SH2D2A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(USBIA3575-01A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A3575-01A
Lokale Artikelnummer::
USBIA3575-01A
Beschreibung:
Anti-ACTR3 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI034501-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
034501-APC
Lokale Artikelnummer::
USBI034501-APC
Beschreibung:
Anti-DCDC2 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-1497R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1497R-A750
Lokale Artikelnummer::
BOSSBS-1497R-A750
Beschreibung:
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15024R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15024R-A555
Lokale Artikelnummer::
BOSSBS-15024R-A555
Beschreibung:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf146 gene product has been provisionally designated C1orf146 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(USBI039063-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
039063-APC
Lokale Artikelnummer::
USBI039063-APC
Beschreibung:
Anti-NOSIP Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI129491)
Lieferant:
US Biological
Hersteller-Artikelnummer::
129491
Lokale Artikelnummer::
USBI129491
Beschreibung:
Anti-MCM10 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-13330R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13330R
Lokale Artikelnummer::
BOSSBS-13330R
Beschreibung:
Anti-GEMIN7 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3131R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3131R-FITC
Lokale Artikelnummer::
BOSSBS-3131R-FITC
Beschreibung:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter. Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP. Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences. Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP. Can activate the transcriptional activity of TFF1. Also mediates membrane-initiated estrogen signaling involving various kinase cascades. Isoform 3 is involved in activation of NOS3 and endothelial nitric oxide production. Isoforms lacking one or several functional domains are thought to modulate transcriptional activity by competitive ligand or DNA binding and/or heterodimerization with the full length receptor. Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3. Isoform 3 can bind to ERE and inhibit isoform 1.
VE:
1 * 100 µl
Artikel-Nr:
(USBID9000-18B-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
D9000-18B-APC
Lokale Artikelnummer::
USBID9000-18B-APC
Beschreibung:
Anti-DRD4 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(ROCK611-1602)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
611-1602
Lokale Artikelnummer::
ROCK611-1602
Beschreibung:
Anti-Rabbit IgG whole molecule is suitable for use in immunoelectrophoresis, western-blot, competitive western-blot, ELISA and competitive ELISA assays. Specific conditions for reactivity and signal detection should be optimized by the end user.
VE:
1 * 2 mg
Artikel-Nr:
(BOSSBS-7639R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7639R-A350
Lokale Artikelnummer::
BOSSBS-7639R-A350
Beschreibung:
SLC14A1 is one of two major mammalian urea transporters, which play a critical role in the urine-concentrating mechanism. Their abundance is regulated by vasopressin, glucocorticoids, and mineralocorticoids. These regulatory mechanisms may be important in disease states such as diabetes.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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