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PROSCI
Artikel-Nr:
(PRSI19-449)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-449
Lokale Artikelnummer::
PRSI19-449
Beschreibung:
Anti-SAR1B Rabbit Polyclonal Antibody
VE:
1 * 100 µl
New Product
Artikel-Nr:
(PRSI6001)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6001
Lokale Artikelnummer::
PRSI6001
Beschreibung:
TRIP6 Antibody: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kappa B activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-180)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-180
Lokale Artikelnummer::
PRSI36-180
Beschreibung:
Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized receptors, the DD-containing adaptor molecule FADD, procaspase-8, procaspase-10 and c-FLIP. The DISC structure provides a platform for the oligomerization of procaspase-8 that allows two procaspase-8 homodimers to be in the close proximity leading to the initial activation of procaspase-8. At the first cleavage step, the N-terminal p43/p41 and the C-terminal p30 cleavage products are generated. Importantly, these cleavage products already possess catalytic activity. At the second cleavage step, p43/p41 and p30 are processed to p10 and p20, respectively, which leads to the generation of the active caspase-8 heterotetramer (p20/p10)2.
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXP-5707-M)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5707-M
Lokale Artikelnummer::
PRSIXP-5707-M
Beschreibung:
Anti-IL11 Mouse Monoclonal Antibody [clone: 27B1047.1]
VE:
1 * 500 µG
Artikel-Nr:
(PRSI18-917)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
18-917
Lokale Artikelnummer::
PRSI18-917
Beschreibung:
Anti-CDH2 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI19-443)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-443
Lokale Artikelnummer::
PRSI19-443
Beschreibung:
Anti-KCNIP1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI90-371)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-371
Lokale Artikelnummer::
PRSI90-371
Beschreibung:
B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production and generation of alloreactive cytotoxic T cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumour cancer cells. The role of B7-H4 in tumour progression may be to transform precancerous cells and then protect them from immunosurveillance.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-674)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-674
Lokale Artikelnummer::
PRSI42-674
Beschreibung:
Anti-MPV17 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI90-478)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-478
Lokale Artikelnummer::
PRSI90-478
Beschreibung:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI29-062)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-062
Lokale Artikelnummer::
PRSI29-062
Beschreibung:
NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-121)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-121
Lokale Artikelnummer::
PRSI45-121
Beschreibung:
Anti-PRDM10 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI62-326)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-326
Lokale Artikelnummer::
PRSI62-326
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI33-809)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-809
Lokale Artikelnummer::
PRSI33-809
Beschreibung:
Epithelial cellular adhesion molecule (EpCAM), is also identified as epithelial specific antigen (ESA) and the 40 kDa transmembrane epithelial glycoprotein EGP40. EpCAM is expressed on the baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. The VU-1D9 antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. EpCAM antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI49-890)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-890
Lokale Artikelnummer::
PRSI49-890
Beschreibung:
Recognizes human ORAI3, also known as Transmembrane protein 142C (TMEM142C), a 31.5 kDa multi-pass membrane protein belonging to the ORAI family. Antigen stimulation of immune cells triggers Ca2+ entry through Ca2+ release-activated Ca2+ (CRAC) channels. CRAC channels are the main pathway for Ca2+ influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. ORAI3 is one of two mammalian homologs of ORAI1, a four- transmembrane spanning protein that is an essential component of CRAC channels. ORAI3, along with ORAI1 and ORAI2, functions as a Ca2+ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca2+ sensor. Studies indicate that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Is not expected to cross react with either ORAI1 or ORAI2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5987P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5987P
Lokale Artikelnummer::
PRSI5987P
Beschreibung:
KPNA4 peptide is used for blocking the activity of KPNA4 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-802)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-802
Lokale Artikelnummer::
PRSI30-802
Beschreibung:
WASF3 is a member of the Wiskott-Aldrich syndrome protein family. It is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function.This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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