Antikörper
Artikel-Nr:
(USBI031751-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031751-PE
Lokale Artikelnummer::
USBI031751-PE
Beschreibung:
Anti-AKT1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes an antigen associated with the nuclear membrane in human cells. It can be used to stain the nuclear membrane in cell or tissue preparations and can be used as a marker of the nuclear membrane in subcellular fractions. It produces a ring pattern around the nucleus of cells of normal and malignant cells and may be used to stain the nuclear membrane of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.,The nuclear envelope (also known as the perinuclear envelope, nuclear membrane, nucleolemma or karyotheca) is the double membrane of the nucleus that encloses genetic material in eukaryotic cells. It separates the contents of the nucleus (DNA in particular) from the cytosol (cytoplasm). Numerous nuclear pores are present on the nuclear envelope to facilitate and regulate the exchange of materials (for example, proteins and RNA) between the nucleus and the cytoplasm. The space between the two membranes that make up the nuclear envelope is called the perinuclear space (also called the perinuclear cisterna), and is usually about 20 - 40 nm wide. Each of the two membranes is composed of a lipid bilayer. The outer membrane is continuous with the rough endoplasmic reticulum. The inner membrane is erected upon the nuclear lamina, a network of intermediate filaments made of lamin, that plays a role in mitosis and meiosis. The type of lamins present are A, B1, B2, and C. The nuclear envelope may also play a role in the disposition of chromatin inside the nucleus. The lamina acts as a site of attachment for chromosomes. It also acts like a shield for the nucleus. During prophase in mitosis, the chromatids begin condensing to form chromosomes, and the nuclear envelope begins to disintegrate. During metaphase, the nuclear envelope is completely disintegrated, and the chromosomes can be pulled apart as chromatids by the spindle fibers.
Artikel-Nr:
(ABGEAP16321C)
Lieferant:
Abgent
Hersteller-Artikelnummer::
AP16321C
Lokale Artikelnummer::
ABGEAP16321C
Beschreibung:
LEAF (Low Endotoxin, Azide-Free)
VE:
1 * 400 µl
Artikel-Nr:
(USBI042458-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042458-APC
Lokale Artikelnummer::
USBI042458-APC
Beschreibung:
Anti-SULT1A2 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-0069R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0069R-HRP
Lokale Artikelnummer::
BOSSBS-0069R-HRP
Beschreibung:
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
VE:
1 * 100 µl
Artikel-Nr:
(USBIL1005-02F)
Lieferant:
US Biological
Hersteller-Artikelnummer::
L1005-02F
Lokale Artikelnummer::
USBIL1005-02F
Beschreibung:
Anti-Lactalbumin, alpha Rabbit Polyclonal Antibody (FITC (Fluorescein))
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-3318R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3318R-HRP
Lokale Artikelnummer::
BOSSBS-3318R-HRP
Beschreibung:
The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8060R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8060R
Lokale Artikelnummer::
BOSSBS-8060R
Beschreibung:
Anti-SAMHD1 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12565R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12565R-A647
Lokale Artikelnummer::
BOSSBS-12565R-A647
Beschreibung:
ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
VE:
1 * 100 µl
Artikel-Nr:
(ABGEAP14224A)
Lieferant:
Abgent
Hersteller-Artikelnummer::
AP14224A
Lokale Artikelnummer::
ABGEAP14224A
Beschreibung:
Anti-PDIA4 Rabbit Polyclonal Antibody
VE:
1 * 400 µl
Artikel-Nr:
(USBIC8923-50A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C8923-50A
Lokale Artikelnummer::
USBIC8923-50A
Beschreibung:
Anti-CYLD Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-2434R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2434R-CY7
Lokale Artikelnummer::
BOSSBS-2434R-CY7
Beschreibung:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2439R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2439R-A350
Lokale Artikelnummer::
BOSSBS-2439R-A350
Beschreibung:
Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tumor suppressor. Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7. Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development.
VE:
1 * 100 µl
Artikel-Nr:
(USBI040377-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040377-AP
Lokale Artikelnummer::
USBI040377-AP
Beschreibung:
Anti-PQLC2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBIL2192-30)
Lieferant:
US Biological
Hersteller-Artikelnummer::
L2192-30
Lokale Artikelnummer::
USBIL2192-30
Beschreibung:
Anti-Light Chains Pig Polyclonal Antibody
VE:
1 * 1 mL
Artikel-Nr:
(USBIP9003-01C-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9003-01C-HRP
Lokale Artikelnummer::
USBIP9003-01C-HRP
Beschreibung:
Anti-PRKDC Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Preis auf Anfrage
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-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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