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3-Fluoro-4-methylbenzenecarboximidamide+hydrochloride
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3-Fluoro-4-methylbenzenecarboximidamide+hydrochloride
Artikel-Nr:
(BOSSBS-11329R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11329R-A680
Lokale Artikelnummer::
BOSSBS-11329R-A680
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukaemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11329R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11329R-A488
Lokale Artikelnummer::
BOSSBS-11329R-A488
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3071R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3071R-A350
Lokale Artikelnummer::
BOSSBS-3071R-A350
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11844R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11844R-A555
Lokale Artikelnummer::
BOSSBS-11844R-A555
Beschreibung:
GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10351R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10351R-A555
Lokale Artikelnummer::
BOSSBS-10351R-A555
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12904R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12904R-A488
Lokale Artikelnummer::
BOSSBS-12904R-A488
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
Lieferant:
Biotium
Beschreibung:
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
Artikel-Nr:
(BLDPBD146258-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD146258-5G
Lokale Artikelnummer::
BLDPBD146258-5G
Beschreibung:
o-Phenylendiacetonitril 98%
VE:
1 * 5 g
Artikel-Nr:
(ABCAAB28327-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB28327-100
Lokale Artikelnummer::
ABCAAB28327-100
Beschreibung:
Anti-HLA DR Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: MEM-12]
VE:
1 * 100 Tests
 This is a MarketSource item. Additional charges may apply
Lieferant:
Thermo Scientific
Beschreibung:
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethanol 98%
Artikel-Nr:
(ABCAAB276046-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB276046-100
Lokale Artikelnummer::
ABCAAB276046-100
Beschreibung:
Anti-OLFM4 Mouse Monoclonal Antibody [clone: 12]
VE:
1 * 100 µl
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ABCAAB95731-50)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB95731-50
Lokale Artikelnummer::
ABCAAB95731-50
Beschreibung:
Anti-MCSF Receptor Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: 12-3A3-1B10]
VE:
1 * 50 Tests
This is a MarketSource item. Additional charges may apply
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Methoxyphenylboronsäurepinakolester
Artikel-Nr:
(BLDPBD81798-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD81798-1G
Lokale Artikelnummer::
BLDPBD81798-1G
Beschreibung:
3,4-Dichlorthiophenol 98%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-3729R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3729R-A750
Lokale Artikelnummer::
BOSSBS-3729R-A750
Beschreibung:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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