Methyl+3-bromo-2-chloro-6-fluorobenzoate
Artikel-Nr:
(BLDPBD00799087-25M)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD00799087-25M
Lokale Artikelnummer::
BLDPBD00799087-25M
Beschreibung:
Fmoc-4-methoxy-L-homophenylalanine 95%
VE:
1 * 25 mg
Artikel-Nr:
(BOSSBS-1979R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1979R-CY5
Lokale Artikelnummer::
BOSSBS-1979R-CY5
Beschreibung:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11434R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11434R
Lokale Artikelnummer::
BOSSBS-11434R
Beschreibung:
Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1979R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1979R-A750
Lokale Artikelnummer::
BOSSBS-1979R-A750
Beschreibung:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1979R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1979R-A555
Lokale Artikelnummer::
BOSSBS-1979R-A555
Beschreibung:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0819R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0819R-A555
Lokale Artikelnummer::
BOSSBS-0819R-A555
Beschreibung:
Tyrosinase is the key enzyme for melanin,synthesis in mammalian melanocytes and has been considered to be a unique marker for the study of melanocyte differentiation. A cDNA library was constructed from poly(A)+ mRNA from mouse melanocytes and screened using anti- tyrosinase antiserum and oligonucleotide probes corresponding to amino acid sequence of tyrosinase. sequencing of some cDNA clones positive in these screenings gave a nucleotide sequence of 1838 nucleotides including a open reading frame of 1344 nucleotides that was found to correspond exactly to the amino acid sequence of the cyanogen bromide fragments of tyrosinase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5218R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5218R-A350
Lokale Artikelnummer::
BOSSBS-5218R-A350
Beschreibung:
Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Methoxy-L-tryptophan
Artikel-Nr:
(BOSSBS-11434R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11434R-A555
Lokale Artikelnummer::
BOSSBS-11434R-A555
Beschreibung:
Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11434R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11434R-CY3
Lokale Artikelnummer::
BOSSBS-11434R-CY3
Beschreibung:
Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6382R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6382R
Lokale Artikelnummer::
BOSSBS-6382R
Beschreibung:
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3405R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3405R-CY7
Lokale Artikelnummer::
BOSSBS-3405R-CY7
Beschreibung:
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6382R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6382R-CY3
Lokale Artikelnummer::
BOSSBS-6382R-CY3
Beschreibung:
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6382R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6382R-CY5
Lokale Artikelnummer::
BOSSBS-6382R-CY5
Beschreibung:
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5218R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5218R-FITC
Lokale Artikelnummer::
BOSSBS-5218R-FITC
Beschreibung:
Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7951R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7951R-A680
Lokale Artikelnummer::
BOSSBS-7951R-A680
Beschreibung:
The function of ADCK1 is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
VE:
1 * 100 µl
Preis auf Anfrage
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