(1R,5S)-8-Azabicyclo[3.2.1]octan-3-one
Lieferant:
Sigma-Aldrich
Beschreibung:
Forskolin (aus Coleus forskohlii), Sigma-Aldrich®
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD115 (CSF-1R) Rat Monoclonal Antibody [clone: 9-4D2-1E4] (APC (Allophycocyanin))
Artikel-Nr:
(EHERC13794000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C13794000
Lokale Artikelnummer::
EHERC13794000
Beschreibung:
1-Fluornaphthalin
VE:
1 * 0,5 g
Artikel-Nr:
(SIAL56481-10X25DIS)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
56481-10X25DIS
Lokale Artikelnummer::
SIAL56481-10X25DIS
Beschreibung:
D(+)-Cellobiose, Millipore®
VE:
1 * 10 SET
Artikel-Nr:
(HEWL18713-60040)
Lieferant:
Agilent
Hersteller-Artikelnummer::
18713-60040
Lokale Artikelnummer::
HEWL18713-60040
Beschreibung:
The micro ECD has a detection zone volume 10 times smaller than any other ECD with replicable inlet liner to decreasing column contamination of the cell.
VE:
1 * 1 ST
Lieferant:
Alfa Aesar
Beschreibung:
3'-Desoxythymidin (2',3'-Didesoxythymidin)
Lieferant:
Cayman Chemical
Beschreibung:
Alfacalcidol ≥95%, kristalliner Feststoff
Lieferant:
MP Biomedicals
Beschreibung:
(-)-trans-Caryophyllene is a natural bicyclic sesquiterpene that is a constituent of many essential oils.
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD115 (CSF-1R) Rat Monoclonal Antibody [clone: 9-4D2-1E4] (Alexa Fluor® 488)
Artikel-Nr:
(BOSSBS-6464R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6464R-HRP
Lokale Artikelnummer::
BOSSBS-6464R-HRP
Beschreibung:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus, resulting in transcriptional activation of type I IFN genes, which drive the cell in an antiviral state. When sumoylated, translocates to the nucleus and phosphorylates STAT3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3194R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3194R-A350
Lokale Artikelnummer::
BOSSBS-3194R-A350
Beschreibung:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus, resulting in transcriptional activation of type I IFN genes, which drive the cell in an antiviral state. When sumoylated, translocates to the nucleus and phosphorylates STAT3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10181R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10181R-HRP
Lokale Artikelnummer::
BOSSBS-10181R-HRP
Beschreibung:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus, resulting in transcriptional activation of type I IFN genes, which drive the cell in an antiviral state. When sumoylated, translocates to the nucleus and phosphorylates STAT3 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3194R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3194R-HRP
Lokale Artikelnummer::
BOSSBS-3194R-HRP
Beschreibung:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus, resulting in transcriptional activation of type I IFN genes, which drive the cell in an antiviral state. When sumoylated, translocates to the nucleus and phosphorylates STAT3.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
D-Amygdalin 98%
Artikel-Nr:
(BLEG135515)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
135515
Lokale Artikelnummer::
BLEG135515
Beschreibung:
Anti-CD115 (CSF-1R) Rat Monoclonal Antibody [clone: AFS98] (Brilliant Violet® 711)
VE:
1 * 50 µG
![]()
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD115 (CSF-1R) Rat Monoclonal Antibody [clone: AFS98] (Alexa Fluor® 647)
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||