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(1R,5S)-8-Azabicyclo[3.2.1]octan-3-one
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(1R,5S)-8-Azabicyclo[3.2.1]octan-3-one
Artikel-Nr:
(BOSSBS-11262R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11262R-CY7
Lokale Artikelnummer::
BOSSBS-11262R-CY7
Beschreibung:
MP21 is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway. TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane. It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex. In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ?secretase activity. Two isoforms, namely TMP21-I and TMP21-II, exist for this protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0400R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0400R
Lokale Artikelnummer::
BOSSBS-0400R
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalysing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11715R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11715R-CY3
Lokale Artikelnummer::
BOSSBS-11715R-CY3
Beschreibung:
CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1982R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1982R
Lokale Artikelnummer::
BOSSBS-1982R
Beschreibung:
MCM3 is one of the highly conserved mini-chromosome maintenance proteins that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0400R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0400R-CY5
Lokale Artikelnummer::
BOSSBS-0400R-CY5
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0874R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0874R-HRP
Lokale Artikelnummer::
BOSSBS-0874R-HRP
Beschreibung:
The DEK gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA which then induces positive supercoils into closed circular DNA, and is also involved during mRNA processing in splice site selection. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9603R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9603R-CY5.5
Lokale Artikelnummer::
BOSSBS-9603R-CY5.5
Beschreibung:
TEF-3, is a 427 amino acid member of the transcriptional enhancer factor (TEF) family of proteins that are characterized by the presence of a TEA DNA-binding domain. Localized to the nucleus and expressed primarily in skeletal muscle, TEF-3 functions as a transcriptional regulator by binding specifically and non-cooperatively to the M-CAT motif found in the promotors of muscle-specific genes, thereby directing their subsequent expression. TEF-3 contains one TEA DNA-binding domain and is expressed as multiple isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9603R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9603R-CY7
Lokale Artikelnummer::
BOSSBS-9603R-CY7
Beschreibung:
TEF-3, is a 427 amino acid member of the transcriptional enhancer factor (TEF) family of proteins that are characterized by the presence of a TEA DNA-binding domain. Localized to the nucleus and expressed primarily in skeletal muscle, TEF-3 functions as a transcriptional regulator by binding specifically and non-cooperatively to the M-CAT motif found in the promotors of muscle-specific genes, thereby directing their subsequent expression. TEF-3 contains one TEA DNA-binding domain and is expressed as multiple isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-A350
Lokale Artikelnummer::
BOSSBS-13475R-A350
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-FITC
Lokale Artikelnummer::
BOSSBS-13475R-FITC
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9206R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9206R
Lokale Artikelnummer::
BOSSBS-9206R
Beschreibung:
GDE3, also known as glycerophosphodiester phosphodiesterase 3, glycerophosphodiester phosphodiesterase domain containing 2 (GDPD2) or osteoblast differentiation promoting factor (OBDPF), is a 539 amino acid protein belonging to the glycerophosphoryl diester phosphodiesterase family. Possessing glycerophosphoinositol inositolphosphodiesterase activity, GDE3 hydrolyzes glycerophosphoinositol to form inositol 1-phosphate and glycerol, and is suggested to play a role in Actin cytoskeleton remodeling and osteoblast differentiation and growth. A multi-pass membrane protein, GDE3 localizes to cell membrane and cytoplasm, and colocalizes with actin in the cytoskeleton. GDE3 contains one GDPD domain, binds calcium as a cofactor and is encoded by a gene mapping to human chromosome Xq13.1.
VE:
1 * 100 µl
Lieferant:
GE Healthcare - Hyclone
Beschreibung:
Minimum Essential Medium (MEM) is one of the earliest modifications of Basal Medium Eagle (BME) containing amino acid concentrations that more closely mimic those found in mammalian cells. MEM has been used with serum supplementation on a broad range of cell types including suspension and adherent mammalian cells, HeLa, BHK-21, HEK-293, HEp-2, HT-1080, MCF-7,fibroblasts and primary rat astrocytes.
Lieferant:
Alfa Aesar
Beschreibung:
α,α,α-Trifluoracetophenon ≥98%
Artikel-Nr:
(BSENM-1376-250)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
M-1376-250
Lokale Artikelnummer::
BSENM-1376-250
Beschreibung:
Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. GAPDH may have other roles in the activation of transcription and in the regulation of apoptosis as well as Alzheimer's disease and Huntington's disease. The immunogen used to raise this particular antibody was extensively purified pig GAPDH. This antibody can be used as a loading control for western blotting experiments, allowing comparison between the level of this protein and others in a cell or tissue.
VE:
1 * 250 µl
Artikel-Nr:
(BOSSBS-0235R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0235R-CY7
Lokale Artikelnummer::
BOSSBS-0235R-CY7
Beschreibung:
PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3561R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3561R
Lokale Artikelnummer::
BOSSBS-3561R
Beschreibung:
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcriptional activity of the nuclear receptor with which they associate. One such coactivator is KAT13C / nuclear receptor coactivator 2 (NCOA2), also termed Glucocorticoid receptor-interacting protein 1 (GRIP1).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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