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(2R)-1-Azabicyclo[2.2.2]octane-2-carbonitrile
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(2R)-1-Azabicyclo[2.2.2]octane-2-carbonitrile
Artikel-Nr:
(PRSI92-169)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-169
Lokale Artikelnummer::
PRSI92-169
Beschreibung:
Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signalling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. ISG15 becomes conjugated to a diverse set of proteins after IFN-alpha/beta stimulation or microbial challenge. The functions or biochemical consequences ISG15 conjugation to proteins are not yet known, but it appears that this modification does not target proteins for proteasomal degradation. ISG15 shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic factors. Upon interferon treatment, ISG15 can be detected in both free and conjugated forms and is secreted from monocytes and lymphocytes where it can function as a cytokine. In the cell, ISG15 co-localises with intermediate filaments and ISGylation may modulate the JAK-STAT pathway or certain aspects of neurological disease.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-029)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-029
Lokale Artikelnummer::
PRSI91-029
Beschreibung:
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial cells. TNFSF15 is also able to regulate the expression of several important genes involved in angiogenesis. These findings are consistent with the view that TNFSF15 functions as an autocrine cytokine to inhibit angiogenesis and stabilize the vasculature.
VE:
1 * 50 µG
Lieferant:
AIR LIQUIDE CRYOTECHNIC
Beschreibung:
Diese Gefäße sind für die Langzeitlagerung biologischer Proben in Pailletten, Kryo-Röhrchen und Beuteln konzipiert. Eine Vielzahl elektronischer Optionen bei allen Modellen Rack- oder Kanister-Aufbewahrungssysteme für die Proben.
Aus Aluminium und Verbundwerkstoffen hergestellt.
Artikel-Nr:
(PRSI2101)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2101
Lokale Artikelnummer::
PRSI2101
Beschreibung:
GPR15 Antibody: Human immunodeficiency virus (HIV) and related viruses require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo, respectively, ) were recently cloned. This novel G protein-coupled receptor serves as corecptor for simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 has not been identified yet.
VE:
1 * 100 µG
Lieferant:
EUTECH
Beschreibung:
These rugged and user-friendly testers feature a simultaneous display of pH and temperature and provide accurate measurements for water analysis. Available in a standard version or with a spear tip open pore sensor for direct measurements of solid or semi-solid samples such as cheese, meat, fruit, bread and more.
Artikel-Nr:
(BIBBSSD102K)
Lieferant:
SciLabware
Hersteller-Artikelnummer::
SSD102K
Lokale Artikelnummer::
BIBBSSD102K
Beschreibung:
Spare keys for stopckocks, made of borosilicate glass.
VE:
1 * 1 ST
Artikel-Nr:
(171-0872)
Lieferant:
ELGA LabWater
Hersteller-Artikelnummer::
PF2XXXXM1
Lokale Artikelnummer::
ELGAPF2XXXXM1
Beschreibung:
The PURELAB flex 2 uniquely combines ease of use with the accurate delivery of pure water. The flexible modular system can be configured to deliver the quality of water you need for your applications and includes UV photo-oxidation and TOC monitoring. Delivers up to two liters per minute of type I water.
VE:
1 * 1 ST
Artikel-Nr:
(PRSI7529)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7529
Lokale Artikelnummer::
PRSI7529
Beschreibung:
BHLHA15 (basic helix-loop-helix protein 15), also known as MIST1 (muscle intestine and stomach expression 1) belongs to the bHLH family of transcription factors and plays a role in regulating the transcriptional activity of MYOD1 in muscle cell development as well as serving as a key regulator of acinar cell function (1,2). BHLHA15 contains a basic helix-loop-helix (bHLH) domain and is capable of binding to E-box motifs as a homodimer or a heterodimer with E-proteins. It may also negatively regulate bHLH-mediated transcription through a N-terminal repressor domain. It is expressed in mammary epithelial cells and is essential for the regulation of mammary gland development.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI38-149)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-149
Lokale Artikelnummer::
PRSI38-149
Beschreibung:
A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
VE:
1 * 100 µG
Artikel-Nr:
(AXYGAP-20-P)
Lieferant:
Corning
Hersteller-Artikelnummer::
AP-20-P
Lokale Artikelnummer::
AXYGAP-20-P
Beschreibung:
The Axypet™ pro pipettors have been engineered to provide the highest levels of comfort, accuracy and precision. Lightweight construction, contoured shape of the handle and four digit counter were designed to guarantee comfortable pipetting. All pipettors feature smooth plunger movement and extremely low pipetting forces to reduce the wrist strain and fatigue (RSI). Color-coded push buttons help to identify the size of the pipettor.
VE:
1 * 1 ST
Lieferant:
OHAUS
Beschreibung:
These digital heavy duty orbital shakers are designed for a wide range of applications, including cell cultures, that require accurate and repeatable results. The microprocessor control provides consistent uniform shaking while safely ramping to the set speed. Ideal for cell cultures, solubility studies, and extraction procedures. The large capacity shakers have a more powerful drive mechanism and larger orbits for optimal shaking of large vessels.
Artikel-Nr:
(521-4008)
Lieferant:
JOUAN
Hersteller-Artikelnummer::
11177361
Lokale Artikelnummer::
JOUA11177361
Beschreibung:
Adapter 4x15 ml konisch, Ø 17 mm (6 Stück), Für: Thermo Scientific Jouan KR25i
VE:
1 * 6 ST
Lieferant:
Edmund Bühler GmbH
Beschreibung:
Tischschüttler, reziprok; geeignet für Dauerbetrieb und eine Beladung bis 30 kg. Das Universaltablar kann max. 11×1000 bzw. 15×500ml Kolben aufnehmen, das Combifix Rack-System bietet Platz für 6×1000 ml bzw. 12×500ml Erlenmeyerkolben. Durch Auswahl aus dem Sortiment optionaler Aufsätze können viele verschiedene Gefäße aufgenommen werden.
Lieferant:
REVCO TECHNOLOGIES
Beschreibung:
With precise temperature control and stability of all culture parameters, the Series 8000 direct-heat CO₂ incubators offer dependable flexibility for growing cells. The automatic high-temperature decontamination cycle is ideal for overnight sterilisation and ensures consistent sterilisation time after time. Units are light weight and easy to move with accessory roller base, there is a choice of TC or IR CO₂ sensor.
Artikel-Nr:
(FITZ20-AR05)
Lieferant:
Fitzgerald Industries
Hersteller-Artikelnummer::
20-AR05
Lokale Artikelnummer::
FITZ20-AR05
Beschreibung:
Human serum albumin is the most abundant protein in human blood plasma. It is produced in the liver. Albumin comprises about half of the blood serum protein. It is soluble and monomeric. The gene for albumin is located on chromosome 4 and mutations in this gene can result in various anomalous proteins. The human albumin gene is 16,961 nucleotides long from the putative ?cap? site to the first poly(A) addition site. It is split into 15 exons that are symmetrically placed within the 3 domains thought to have arisen by triplication of a single primordial domain.
VE:
1 * 1 mL
Lieferant:
EPPENDORF
Beschreibung:
PICASO (PipetteCalibrationSoftware) is a program for the automatic input and processing of measuring data from the gravimetric or photometric pipette test. With PICASO, all types of pipettes and other dispensers (e.g. bottle-top dispensers) can be checked.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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