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1,3-Bis(3-aminophenoxy)benzol
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1,3-Bis(3-aminophenoxy)benzol
Artikel-Nr:
(USBI126763)
Lieferant:
US Biological
Hersteller-Artikelnummer::
126763
Lokale Artikelnummer::
USBI126763
Beschreibung:
Anti-FGF1 Mouse Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1302R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1302R-HRP
Lokale Artikelnummer::
BOSSBS-1302R-HRP
Beschreibung:
Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6294R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6294R-A555
Lokale Artikelnummer::
BOSSBS-6294R-A555
Beschreibung:
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
VE:
1 * 100 µl
Artikel-Nr:
(USBI038941)
Lieferant:
US Biological
Hersteller-Artikelnummer::
038941
Lokale Artikelnummer::
USBI038941
Beschreibung:
Anti-NFKBIB Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-1302R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1302R-CY3
Lokale Artikelnummer::
BOSSBS-1302R-CY3
Beschreibung:
Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1302R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1302R-A750
Lokale Artikelnummer::
BOSSBS-1302R-A750
Beschreibung:
Glutamic Acid Decarboxylase (GAD) catalyses the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6294R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6294R-A647
Lokale Artikelnummer::
BOSSBS-6294R-A647
Beschreibung:
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13389R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13389R-A750
Lokale Artikelnummer::
BOSSBS-13389R-A750
Beschreibung:
Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex. Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit. The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus. The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells. Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus, Glucosidase IIb retains the complete complex in the ER.
VE:
1 * 100 µl
Artikel-Nr:
(USBI031183-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031183-AP
Lokale Artikelnummer::
USBI031183-AP
Beschreibung:
Anti-PDGFRB Mouse Monoclonal Antibody (AP (Alkaline Phosphatase)) [clone: 275CT1]
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-6294R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6294R-A350
Lokale Artikelnummer::
BOSSBS-6294R-A350
Beschreibung:
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4995R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4995R-A350
Lokale Artikelnummer::
BOSSBS-4995R-A350
Beschreibung:
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7665R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7665R-A350
Lokale Artikelnummer::
BOSSBS-7665R-A350
Beschreibung:
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4995R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4995R-HRP
Lokale Artikelnummer::
BOSSBS-4995R-HRP
Beschreibung:
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4047R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4047R-FITC
Lokale Artikelnummer::
BOSSBS-4047R-FITC
Beschreibung:
ACADM protein is a medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The enzyme catalyzes the initial step of the mitochondrial fatty acid beta oxidation pathway. ACADM expression is induced during periods of fasting, when reliance on fatty acids for energy is increased. Clinical phenotypes are associated with ACADM hereditary deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4047R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4047R-A680
Lokale Artikelnummer::
BOSSBS-4047R-A680
Beschreibung:
ACADM protein is a medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The enzyme catalyses the initial step of the mitochondrial fatty acid beta oxidation pathway. ACADM expression is induced during periods of fasting, when reliance on fatty acids for energy is increased. Clinical phenotypes are associated with ACADM hereditary deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10501R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10501R-CY3
Lokale Artikelnummer::
BOSSBS-10501R-CY3
Beschreibung:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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