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Potassium+trifluoro(3-oxocyclopentyl)borate
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Potassium+trifluoro(3-oxocyclopentyl)borate
Artikel-Nr:
(BOSSBS-6465R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6465R-HRP
Lokale Artikelnummer::
BOSSBS-6465R-HRP
Beschreibung:
Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6465R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6465R-A555
Lokale Artikelnummer::
BOSSBS-6465R-A555
Beschreibung:
Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3864R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3864R-A488
Lokale Artikelnummer::
BOSSBS-3864R-A488
Beschreibung:
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1824R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1824R-A647
Lokale Artikelnummer::
BOSSBS-1824R-A647
Beschreibung:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3864R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3864R-A647
Lokale Artikelnummer::
BOSSBS-3864R-A647
Beschreibung:
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1824R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1824R-HRP
Lokale Artikelnummer::
BOSSBS-1824R-HRP
Beschreibung:
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3864R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3864R-A350
Lokale Artikelnummer::
BOSSBS-3864R-A350
Beschreibung:
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8291R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8291R-HRP
Lokale Artikelnummer::
BOSSBS-8291R-HRP
Beschreibung:
Required during spermatogenesis for sperm head elongation and acrosome formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11105R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11105R-CY5
Lokale Artikelnummer::
BOSSBS-11105R-CY5
Beschreibung:
Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5581R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5581R-A750
Lokale Artikelnummer::
BOSSBS-5581R-A750
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11051R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11051R-A647
Lokale Artikelnummer::
BOSSBS-11051R-A647
Beschreibung:
HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3602R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3602R-A350
Lokale Artikelnummer::
BOSSBS-3602R-A350
Beschreibung:
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3464R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3464R-A680
Lokale Artikelnummer::
BOSSBS-3464R-A680
Beschreibung:
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5690R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5690R-CY3
Lokale Artikelnummer::
BOSSBS-5690R-CY3
Beschreibung:
A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0376R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0376R
Lokale Artikelnummer::
BOSSBS-0376R
Beschreibung:
The protein encoded by this gene is an enzyme that synthesises the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyses the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1770R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1770R-CY3
Lokale Artikelnummer::
BOSSBS-1770R-CY3
Beschreibung:
ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. May also play a role in axon growth and the formation of axonal branches.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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