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POLYMER STANDARDS SERVICE
Artikel-Nr:
(BOSSBS-12088R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12088R-CY3
Lokale Artikelnummer::
BOSSBS-12088R-CY3
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13573R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13573R-A680
Lokale Artikelnummer::
BOSSBS-13573R-A680
Beschreibung:
ZBTB39 may be involved in transcriptional regulation. It belongs to the krueppel C2H2-type zinc-finger protein family and contains one BTB (POZ) domain and eight C2H2-type zinc fingers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3834R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3834R-A555
Lokale Artikelnummer::
BOSSBS-3834R-A555
Beschreibung:
MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes. This protein forms homodimers whereas in prokaryotic ribosomes two L7/L12 dimers and one L10 protein form the L8 protein complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7639R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7639R-CY5
Lokale Artikelnummer::
BOSSBS-7639R-CY5
Beschreibung:
SLC14A1 is one of two major mammalian urea transporters, which play a critical role in the urine-concentrating mechanism. Their abundance is regulated by vasopressin, glucocorticoids, and mineralocorticoids. These regulatory mechanisms may be important in disease states such as diabetes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7501R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7501R-A350
Lokale Artikelnummer::
BOSSBS-7501R-A350
Beschreibung:
CO4A2 is one of the six subunits of type IV collagen, the major structural component of basement membranes. CO4A2 fors a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen and is an inhibitor of angiogenesis and tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7501R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7501R-A750
Lokale Artikelnummer::
BOSSBS-7501R-A750
Beschreibung:
CO4A2 is one of the six subunits of type IV collagen, the major structural component of basement membranes. CO4A2 fors a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen and is an inhibitor of angiogenesis and tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0424R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0424R-A750
Lokale Artikelnummer::
BOSSBS-0424R-A750
Beschreibung:
Cleaves collagens of types I, Ii and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1427R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1427R-A680
Lokale Artikelnummer::
BOSSBS-1427R-A680
Beschreibung:
IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1427R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1427R-A750
Lokale Artikelnummer::
BOSSBS-1427R-A750
Beschreibung:
IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6278R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6278R-A680
Lokale Artikelnummer::
BOSSBS-6278R-A680
Beschreibung:
The protein encoded by this gene is a choline dehydrogenase that localises to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterised to date.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11753R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11753R-CY7
Lokale Artikelnummer::
BOSSBS-11753R-CY7
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.
Artikel-Nr:
(BOSSBS-9107R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9107R-FITC
Lokale Artikelnummer::
BOSSBS-9107R-FITC
Beschreibung:
The death domain (DD) superfamily of proteins share one or more of the following domains: the DD, DED (death-effector domain), CARD (caspase-recruitment domain) and PYD (Pyrin domain). Each of these domains is characterized by a canonical death domain fold, which consists of a bundle of five or six antiparallel α-helices. As their names suggest, these domains play prominent roles in programmed cell death. ASC2 (apoptosis-associated speck-like protein containing a CARD 2), also known as Pyrin-only protein 1 or PADD-only protein 1, is an 89 amino acid member of the DD superfamily that contains one Pyrin domain. Localized to the cytoplasm, ASC2 interacts with ASC to modulate NF-κB and pro-caspase-1 regulation. ASC2 is predominantly expressed in monocytes, macrophages and granulocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12381R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12381R-A680
Lokale Artikelnummer::
BOSSBS-12381R-A680
Beschreibung:
CAMSAP1L1 is a 1489 amino acid protein that contains one calponin-homology domain and one CKK domain, which serves to bind microtubules. There are three isoforms of CAMSAP1L1 that are produced as a result of alternative splicing events. The gene encoding CAMSAP1L1 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson's, Gaucher disease and Usher syndrome are also associated with chromosome 1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11704R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11704R
Lokale Artikelnummer::
BOSSBS-11704R
Beschreibung:
AFG3L2 is a multi-pass membrane metalloprotease that contains one AAA (ATPase associated with diverse cellular activities) domain, a zinc-dependent binding motif, an RNA-binding region and an ATP/GTP binding site. Localizing to the mitochondrial membrane, AFG3L2 is ubiquitously expressed with highest expression levels in skeletal muscle and heart. AFG3L2 shares 69% similarity with the yeast Afg3 protein and 49% similarity with Paraplegin, a protein of mitochondria that is thought to be involved in signal transduction and chaperone-like activities. In mitochondria, AFG3L2 forms a complex with Paraplegin that is believed to regulate essential protein quality control. Mutations in the gene encoding either one of these proteins can result in hereditary spastic paraplegia, a degenerative spinal cord disorder that is characterized by muscle spasms, stiffness in the legs and, in some cases, incontinence.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0352R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0352R-A555
Lokale Artikelnummer::
BOSSBS-0352R-A555
Beschreibung:
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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