4-Brom-2-(cyclopentyloxy)anisol
Artikel-Nr:
(REST30207)
Lieferant:
Restek
Hersteller-Artikelnummer::
30207
Lokale Artikelnummer::
REST30207
Beschreibung:
100-octane, low-lead fuel used in piston-type aircraft.
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-2440R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2440R-A647
Lokale Artikelnummer::
BOSSBS-2440R-A647
Beschreibung:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates NCF1 and regulates NADPH oxidase activation after LPS stimulation suggesting a similar mechanism during microbial infections.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2440R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2440R-FITC
Lokale Artikelnummer::
BOSSBS-2440R-FITC
Beschreibung:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates NCF1 and regulates NADPH oxidase activation after LPS stimulation suggesting a similar mechanism during microbial infections.
VE:
1 * 100 µl
Artikel-Nr:
(25539-1ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
25539-1ML
Lokale Artikelnummer::
SUPL25539-1ML
Beschreibung:
Hexylacetat, Supelco®
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-6464R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6464R-CY5.5
Lokale Artikelnummer::
BOSSBS-6464R-CY5.5
Beschreibung:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus, resulting in transcriptional activation of type I IFN genes, which drive the cell in an antiviral state. When sumoylated, translocates to the nucleus and phosphorylates STAT3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6464R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6464R-CY5
Lokale Artikelnummer::
BOSSBS-6464R-CY5
Beschreibung:
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus, resulting in transcriptional activation of type I IFN genes, which drive the cell in an antiviral state. When sumoylated, translocates to the nucleus and phosphorylates STAT3.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Maltotriose is a matrose regulon inducer in <i>Escherichia coli</i>.
Lieferant:
Cayman Chemical
Beschreibung:
3'-Desoxyadenosin (Cordycepin)
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD115 (CSF-1R) Rat Monoclonal Antibody [clone: 9-4D2-1E4] (PE (Phycoerythrin)/Cy7®)
Lieferant:
Sigma-Aldrich
Beschreibung:
Maltohexaose, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
α-D-Glucose, Sigma-Aldrich®
Artikel-Nr:
(PROOMM0317.06)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0317.06
Lokale Artikelnummer::
PROOMM0317.06
Beschreibung:
Sertraline impurity: Imp. C (EP) as hydrochloride
VE:
1 * 100 mg
Artikel-Nr:
(293245-1L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
293245-1L
Lokale Artikelnummer::
HONC293245-1L
Beschreibung:
1-Octanol ≥99%, CHROMASOLV™ für die HPLC, Riedel-de Haën™
VE:
1 * 1 L
Artikel-Nr:
(BLEG135533)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
135533
Lokale Artikelnummer::
BLEG135533
Beschreibung:
Anti-CD115 (CSF-1R) Rat Monoclonal Antibody [clone: AFS98] (TotalSeq™-A0105)
VE:
1 * 10 µG
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Lieferant:
Alfa Aesar
Beschreibung:
Bariumacetat 99,0-102,0% ACS
Lieferant:
Alfa Aesar
Beschreibung:
Florfenicol 98%
Preis auf Anfrage
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