2-(4-Aminophenoxy)benzoic+acid
Artikel-Nr:
(BOSSBS-4104R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4104R
Lokale Artikelnummer::
BOSSBS-4104R
Beschreibung:
Anti-FXYD1 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6856R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6856R-A488
Lokale Artikelnummer::
BOSSBS-6856R-A488
Beschreibung:
Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID.Tissue specificity: Widely expressed with highest levels in heart, brain and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1235R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1235R-HRP
Lokale Artikelnummer::
BOSSBS-1235R-HRP
Beschreibung:
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7048R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7048R-A350
Lokale Artikelnummer::
BOSSBS-7048R-A350
Beschreibung:
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9626R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9626R
Lokale Artikelnummer::
BOSSBS-9626R
Beschreibung:
RPUSD2, is a 545 amino acid member of the pseudouridine synthase rluA family and is encoded by a gene that is located on chromosome 15. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2302R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2302R
Lokale Artikelnummer::
BOSSBS-2302R
Beschreibung:
Catalase is the classical marker for peroxisomes and is the most abundant protein within peroxisomes. It is found in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7608R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7608R-CY7
Lokale Artikelnummer::
BOSSBS-7608R-CY7
Beschreibung:
Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7757R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7757R-A350
Lokale Artikelnummer::
BOSSBS-7757R-A350
Beschreibung:
Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7555R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7555R-A350
Lokale Artikelnummer::
BOSSBS-7555R-A350
Beschreibung:
EphA3 is a member of the Ephrin (Eph) family. The Ephrins and Eph-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the Ephrin A (EphA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the Ephrin B (EphB) class, which are transmembrane proteins. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7509R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7509R-CY7
Lokale Artikelnummer::
BOSSBS-7509R-CY7
Beschreibung:
Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13729R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13729R-CY3
Lokale Artikelnummer::
BOSSBS-13729R-CY3
Beschreibung:
PCLKC (Protocadherin LKC) belongs to the protocadherin gene family, a subgroup of the cadherin superfamily. It is predominantly expressed in liver, kidney and colon tissues, and has a role in contact inhibition at the lateral surface of epithelial cells. It is a candidate tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3171R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3171R-A680
Lokale Artikelnummer::
BOSSBS-3171R-A680
Beschreibung:
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fibre. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibres. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11485R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11485R-A680
Lokale Artikelnummer::
BOSSBS-11485R-A680
Beschreibung:
Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10014R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10014R-A750
Lokale Artikelnummer::
BOSSBS-10014R-A750
Beschreibung:
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9906R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9906R-A750
Lokale Artikelnummer::
BOSSBS-9906R-A750
Beschreibung:
CRHBP is a potent stimulator of synthesis and secretion of preopiomelanocortin derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH binding protein which inactivates CRH and which may prevent inappropriate pituitary adrenal stimulation in pregnancy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11283R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11283R-A680
Lokale Artikelnummer::
BOSSBS-11283R-A680
Beschreibung:
Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). MDGI is highly expressed in the myocardium, skeletal and smooth muscle fibers, lipid and/or steroid synthesizing cells and terminally differentiated epithelia of the respiratory, intestinal and urogenital tracts.
VE:
1 * 100 µl
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