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1,4-Diazabicyclo[2.2.2]octanebis(sulphur+dioxide)adduct
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1,4-Diazabicyclo[2.2.2]octanebis(sulphur+dioxide)adduct
Artikel-Nr:
(BOSSBS-7501R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7501R-A350
Lokale Artikelnummer::
BOSSBS-7501R-A350
Beschreibung:
CO4A2 is one of the six subunits of type IV collagen, the major structural component of basement membranes. CO4A2 fors a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen and is an inhibitor of angiogenesis and tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7501R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7501R-A750
Lokale Artikelnummer::
BOSSBS-7501R-A750
Beschreibung:
CO4A2 is one of the six subunits of type IV collagen, the major structural component of basement membranes. CO4A2 fors a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen and is an inhibitor of angiogenesis and tumor growth.
VE:
1 * 100 µl
Artikel-Nr:
(APOSBISN0108-10MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BISN0108-10MG
Lokale Artikelnummer::
APOSBISN0108-10MG
Beschreibung:
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively, showing no inhibitory activities against 250 other protein kinases observed.
VE:
1 * 10 mg
Artikel-Nr:
(BOSSBS-0424R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0424R-A750
Lokale Artikelnummer::
BOSSBS-0424R-A750
Beschreibung:
Cleaves collagens of types I, Ii and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1427R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1427R-A680
Lokale Artikelnummer::
BOSSBS-1427R-A680
Beschreibung:
IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1427R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1427R-A750
Lokale Artikelnummer::
BOSSBS-1427R-A750
Beschreibung:
IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11753R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11753R-CY7
Lokale Artikelnummer::
BOSSBS-11753R-CY7
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.
Artikel-Nr:
(BOSSBS-9107R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9107R-FITC
Lokale Artikelnummer::
BOSSBS-9107R-FITC
Beschreibung:
The death domain (DD) superfamily of proteins share one or more of the following domains: the DD, DED (death-effector domain), CARD (caspase-recruitment domain) and PYD (Pyrin domain). Each of these domains is characterized by a canonical death domain fold, which consists of a bundle of five or six antiparallel α-helices. As their names suggest, these domains play prominent roles in programmed cell death. ASC2 (apoptosis-associated speck-like protein containing a CARD 2), also known as Pyrin-only protein 1 or PADD-only protein 1, is an 89 amino acid member of the DD superfamily that contains one Pyrin domain. Localized to the cytoplasm, ASC2 interacts with ASC to modulate NF-κB and pro-caspase-1 regulation. ASC2 is predominantly expressed in monocytes, macrophages and granulocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12381R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12381R-A680
Lokale Artikelnummer::
BOSSBS-12381R-A680
Beschreibung:
CAMSAP1L1 is a 1489 amino acid protein that contains one calponin-homology domain and one CKK domain, which serves to bind microtubules. There are three isoforms of CAMSAP1L1 that are produced as a result of alternative splicing events. The gene encoding CAMSAP1L1 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson's, Gaucher disease and Usher syndrome are also associated with chromosome 1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11704R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11704R
Lokale Artikelnummer::
BOSSBS-11704R
Beschreibung:
AFG3L2 is a multi-pass membrane metalloprotease that contains one AAA (ATPase associated with diverse cellular activities) domain, a zinc-dependent binding motif, an RNA-binding region and an ATP/GTP binding site. Localizing to the mitochondrial membrane, AFG3L2 is ubiquitously expressed with highest expression levels in skeletal muscle and heart. AFG3L2 shares 69% similarity with the yeast Afg3 protein and 49% similarity with Paraplegin, a protein of mitochondria that is thought to be involved in signal transduction and chaperone-like activities. In mitochondria, AFG3L2 forms a complex with Paraplegin that is believed to regulate essential protein quality control. Mutations in the gene encoding either one of these proteins can result in hereditary spastic paraplegia, a degenerative spinal cord disorder that is characterized by muscle spasms, stiffness in the legs and, in some cases, incontinence.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0352R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0352R-A555
Lokale Artikelnummer::
BOSSBS-0352R-A555
Beschreibung:
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11669R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11669R-FITC
Lokale Artikelnummer::
BOSSBS-11669R-FITC
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF146 (RING finger protein 146), also known as Dactylidin, is a 359 amino acid protein that contains one RING-type zinc finger and one WWE domain. Via its RING-type zinc finger, RNF146 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF146 are associated with Alzheimer's disease (AD) and may lead to a higher risk of breast cancer. Two isoforms of RNF146 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5889R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5889R-A750
Lokale Artikelnummer::
BOSSBS-5889R-A750
Beschreibung:
HYAL3 is a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7983R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7983R-CY3
Lokale Artikelnummer::
BOSSBS-7983R-CY3
Beschreibung:
The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4289R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4289R-CY7
Lokale Artikelnummer::
BOSSBS-4289R-CY7
Beschreibung:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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