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5-Brom-2-methoxyphenylborons\\u00E4ure
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5-Brom-2-methoxyphenylborons\\u00E4ure
Artikel-Nr:
(BOSSBS-11681R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11681R-A555
Lokale Artikelnummer::
BOSSBS-11681R-A555
Beschreibung:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4775R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4775R-CY5.5
Lokale Artikelnummer::
BOSSBS-4775R-CY5.5
Beschreibung:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11681R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11681R-A488
Lokale Artikelnummer::
BOSSBS-11681R-A488
Beschreibung:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15576R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15576R-A647
Lokale Artikelnummer::
BOSSBS-15576R-A647
Beschreibung:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localises to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12900R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12900R-A350
Lokale Artikelnummer::
BOSSBS-12900R-A350
Beschreibung:
General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12900R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12900R-FITC
Lokale Artikelnummer::
BOSSBS-12900R-FITC
Beschreibung:
General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5981R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5981R
Lokale Artikelnummer::
BOSSBS-5981R
Beschreibung:
p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5168R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5168R-A680
Lokale Artikelnummer::
BOSSBS-5168R-A680
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3028R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3028R-A680
Lokale Artikelnummer::
BOSSBS-3028R-A680
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5141R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5141R-CY5
Lokale Artikelnummer::
BOSSBS-5141R-CY5
Beschreibung:
Matrin 3 (MATR 3) is an internal nuclear matrix protein that may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer MATR 3 may play a role in nuclear retention of defective RNAs. MATR3 forms part of complex consisting of SFPQ, NONO and MATR3.The protein contains 1 matrin type zinc finger and 2 RRM (RNA recognition motif) domains. Two transcript variants encoding the same protein have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0300R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0300R-CY5.5
Lokale Artikelnummer::
BOSSBS-0300R-CY5.5
Beschreibung:
Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9575R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9575R-HRP
Lokale Artikelnummer::
BOSSBS-9575R-HRP
Beschreibung:
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the β-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5168R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5168R-A488
Lokale Artikelnummer::
BOSSBS-5168R-A488
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9575R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9575R-A488
Lokale Artikelnummer::
BOSSBS-9575R-A488
Beschreibung:
The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the β-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-CY5
Lokale Artikelnummer::
BOSSBS-12919R-CY5
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5168R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5168R-A555
Lokale Artikelnummer::
BOSSBS-5168R-A555
Beschreibung:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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