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1-[2-(4-Chlorophenyl)cyclopropyl]ethan-1-one
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1-[2-(4-Chlorophenyl)cyclopropyl]ethan-1-one
Artikel-Nr:
(BOSSBS-15552R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15552R-A750
Lokale Artikelnummer::
BOSSBS-15552R-A750
Beschreibung:
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5215R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5215R-A750
Lokale Artikelnummer::
BOSSBS-5215R-A750
Beschreibung:
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5145R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5145R-A750
Lokale Artikelnummer::
BOSSBS-5145R-A750
Beschreibung:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2367R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2367R-HRP
Lokale Artikelnummer::
BOSSBS-2367R-HRP
Beschreibung:
A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Artikel-Nr:
(BOSSBS-12191R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12191R-A647
Lokale Artikelnummer::
BOSSBS-12191R-A647
Beschreibung:
DZIP3 is a 1,208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in signaling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6901R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6901R-FITC
Lokale Artikelnummer::
BOSSBS-6901R-FITC
Beschreibung:
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENP-T is one of the basic inner kinetochore proteins with most further proteins binding downstream, suggesting a fundamental role of CENP-T in kinetochore function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8327R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8327R-A555
Lokale Artikelnummer::
BOSSBS-8327R-A555
Beschreibung:
Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0874R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0874R-FITC
Lokale Artikelnummer::
BOSSBS-0874R-FITC
Beschreibung:
The DEK gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA which then induces positive supercoils into closed circular DNA, and is also involved during mRNA processing in splice site selection. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13263R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13263R-FITC
Lokale Artikelnummer::
BOSSBS-13263R-FITC
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5713R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5713R-FITC
Lokale Artikelnummer::
BOSSBS-5713R-FITC
Beschreibung:
HOXA5 upregulates both p53 promoter-reporter constructs and endogenous p53 synthesis, leading to apoptosis. HOXA5 is detectable in approximately one-third of primary tumors. Lack of HOXA5 expression strongly correlates with methylation of its promoter region, suggesting a causal role for methylation in the silencing of HOXA5 gene expression. HOXA5 expression is an important step in tumorigenesis and loss of expression of p53 in human breast cancer may be primarily due to lack of expression of HOXA5.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5713R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5713R-A647
Lokale Artikelnummer::
BOSSBS-5713R-A647
Beschreibung:
HOXA5 upregulates both p53 promoter-reporter constructs and endogenous p53 synthesis, leading to apoptosis. HOXA5 is detectable in approximately one-third of primary tumors. Lack of HOXA5 expression strongly correlates with methylation of its promoter region, suggesting a causal role for methylation in the silencing of HOXA5 gene expression. HOXA5 expression is an important step in tumorigenesis and loss of expression of p53 in human breast cancer may be primarily due to lack of expression of HOXA5.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0039R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0039R-A488
Lokale Artikelnummer::
BOSSBS-0039R-A488
Beschreibung:
The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8577R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8577R-A488
Lokale Artikelnummer::
BOSSBS-8577R-A488
Beschreibung:
GPKOW is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0039R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0039R-A555
Lokale Artikelnummer::
BOSSBS-0039R-A555
Beschreibung:
The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4280R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4280R-FITC
Lokale Artikelnummer::
BOSSBS-4280R-FITC
Beschreibung:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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