N\'-[1-Cyclopropylaminopropylidene]hydrazinecarboxylic+acid-tert-
Artikel-Nr:
(APOSOR183432-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR183432-1G
Lokale Artikelnummer::
APOSOR183432-1G
Beschreibung:
2,6-Dimethyl-3-(1H-pyrazol-3-yl)imidazo[1,2-a]pyridine
VE:
1 * 1 g
Artikel-Nr:
(1A00460.)
Lieferant:
USP
Hersteller-Artikelnummer::
1A00460
Lokale Artikelnummer::
USPH1A00460
Beschreibung:
Pharmaceutical Analytical Impurities are released through a USP quality process designed to ensure identity and quality appropriate for analytical applications. These impurities are supported with a product information sheet for each batch.
VE:
1 * 10 mg
Artikel-Nr:
(201901-50G)
Lieferant:
SIGMA ALDRICH MICROSCOPY
Hersteller-Artikelnummer::
201901-50G
Lokale Artikelnummer::
SIAM201901-50G
Beschreibung:
Chrysophenine, Dye content 65 % (Direct Yellow 12)
VE:
1 * 50 g
Artikel-Nr:
(BOSSBS-5560R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5560R-A350
Lokale Artikelnummer::
BOSSBS-5560R-A350
Beschreibung:
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6425R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6425R-A350
Lokale Artikelnummer::
BOSSBS-6425R-A350
Beschreibung:
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6425R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6425R-A680
Lokale Artikelnummer::
BOSSBS-6425R-A680
Beschreibung:
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12405R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12405R-HRP
Lokale Artikelnummer::
BOSSBS-12405R-HRP
Beschreibung:
Mitogen-activated protein kinase (MAPK) signaling pathways involve closely related MAP kinases, including extracellular-signal-related kinase 3 (ERK 3, also designated PRKM6 and p97MAPK). Serum, growth factors and phorbol esters can initiate ERK 3 signaling pathways. Despite lacking a definitive nuclear localization sequence, ERK 3 constitutively localizes to the nucleus upon activation. p38 pathway activation-dependent upregulation of ERK 3 is independent of the status of p53, Bcl-2 and caspase-3 during cell stress and damage induced by proteasome inhibition, suggesting ERK 3 in part mediates intracellular defense or cell rescue. The human ERK 3 gene maps to chromosome 15q21.2 and encodes a 721 amino acid protein.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL21955-25MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
21955-25MG
Lokale Artikelnummer::
SIAL21955-25MG
Beschreibung:
5(6)-Carboxytetramethylrhodamine N-succinimidyl ester (TMR-SE) is used as an amine coupling reagent to form 5(6)-carboxytetramethylrhodamine (TMR) derivatized compounds such as proteins and drugs.
VE:
1 * 25 mg
Artikel-Nr:
(BOSSBS-3145R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3145R
Lokale Artikelnummer::
BOSSBS-3145R
Beschreibung:
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
VE:
1 * 100 µl
Artikel-Nr:
(APOSPC300581-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC300581-1G
Lokale Artikelnummer::
APOSPC300581-1G
Beschreibung:
Ethyl 3-bromo-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl 6-bromo-8-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate
Artikel-Nr:
(BOSSBS-8414R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8414R
Lokale Artikelnummer::
BOSSBS-8414R
Beschreibung:
The hydroxyacylglutathione hydrolase-like protein (HAGHL) is a 290 amino acid protein that belongs to the glyoxalase II family. HAGHL binds two zinc ions per subunit and acts as a hydrolase on ester bonds. The gene encoding HAGHL maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15518R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15518R-CY5
Lokale Artikelnummer::
BOSSBS-15518R-CY5
Beschreibung:
IFITM5 is a membrane protein thought to play a role in bone mineralisation. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195).
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
Cumarin zur Synthese, Sigma-Aldrich®
Lieferant:
VWR Collection
Beschreibung:
Schaumstoffeinsatz, erfordert Universalhalterung, Für: 34 Röhrchen, 12 - 13 mm Ø
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Artikel-Nr:
(BOSSBS-4041R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4041R-FITC
Lokale Artikelnummer::
BOSSBS-4041R-FITC
Beschreibung:
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
VE:
1 * 100 µl
Preis auf Anfrage
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