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1H-Imidazol-2-ylmethanol
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1H-Imidazol-2-ylmethanol
Artikel-Nr:
(APOSOR471616-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR471616-100G
Lokale Artikelnummer::
APOSOR471616-100G
Beschreibung:
L-Arginin-methylester-dihydrochlorid 98%
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-1227R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1227R-CY3
Lokale Artikelnummer::
BOSSBS-1227R-CY3
Beschreibung:
Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes. Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. May be involved both in adult synaptic function and plasticity and in brain development. Activates AKT1 by phosphorylating it on 'Tyr-176'. Phosphorylates AR on 'Tyr-267' and 'Tyr-363' thereby promoting its recruitment to androgen-responsive enhancers (AREs). Phosphorylates WWOX on 'Tyr-287'. Phosphorylates MCF2, thereby enhancing its activity as a guanine nucleotide exchange factor (GEF) toward Rho family proteins. Contributes to the control of AXL receptor levels. Confers metastatic properties on cancer cells and promotes tumor growth by negatively regulating tumor suppressor such as WWOX and positively regulating pro-survival factors such as AKT1 and AR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0392R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0392R-A680
Lokale Artikelnummer::
BOSSBS-0392R-A680
Beschreibung:
Sequence: H-Arg-Lys-Asp-Val-Tyr-OH<br> MW: 679,8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0392R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0392R-A488
Lokale Artikelnummer::
BOSSBS-0392R-A488
Beschreibung:
Sequence:: H-Arg-Lys-Asp-Val-Tyr-OH
MW: 679.8
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1227R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1227R-A647
Lokale Artikelnummer::
BOSSBS-1227R-A647
Beschreibung:
Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes. Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. May be involved both in adult synaptic function and plasticity and in brain development. Activates AKT1 by phosphorylating it on 'Tyr-176'. Phosphorylates AR on 'Tyr-267' and 'Tyr-363' thereby promoting its recruitment to androgen-responsive enhancers (AREs). Phosphorylates WWOX on 'Tyr-287'. Phosphorylates MCF2, thereby enhancing its activity as a guanine nucleotide exchange factor (GEF) toward Rho family proteins. Contributes to the control of AXL receptor levels. Confers metastatic properties on cancer cells and promotes tumor growth by negatively regulating tumor suppressor such as WWOX and positively regulating pro-survival factors such as AKT1 and AR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1227R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1227R-FITC
Lokale Artikelnummer::
BOSSBS-1227R-FITC
Beschreibung:
Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes. Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. May be involved both in adult synaptic function and plasticity and in brain development. Activates AKT1 by phosphorylating it on 'Tyr-176'. Phosphorylates AR on 'Tyr-267' and 'Tyr-363' thereby promoting its recruitment to androgen-responsive enhancers (AREs). Phosphorylates WWOX on 'Tyr-287'. Phosphorylates MCF2, thereby enhancing its activity as a guanine nucleotide exchange factor (GEF) toward Rho family proteins. Contributes to the control of AXL receptor levels. Confers metastatic properties on cancer cells and promotes tumor growth by negatively regulating tumor suppressor such as WWOX and positively regulating pro-survival factors such as AKT1 and AR.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
L-Arginin-methylester-dihydrochlorid 98%
Artikel-Nr:
(BOSSBS-5218R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5218R-CY3
Lokale Artikelnummer::
BOSSBS-5218R-CY3
Beschreibung:
Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
L-Glutaminsäure-dimethylester-hydrochlorid 99%, rein
Artikel-Nr:
(APOSOR912136-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR912136-100G
Lokale Artikelnummer::
APOSOR912136-100G
Beschreibung:
(S)-Methyl-2-hydroxy-3-phenylpropanoate 98%
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-8012R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8012R-A555
Lokale Artikelnummer::
BOSSBS-8012R-A555
Beschreibung:
The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7951R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7951R-A488
Lokale Artikelnummer::
BOSSBS-7951R-A488
Beschreibung:
The function of ADCK1 is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8012R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8012R-A680
Lokale Artikelnummer::
BOSSBS-8012R-A680
Beschreibung:
The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8012R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8012R-FITC
Lokale Artikelnummer::
BOSSBS-8012R-FITC
Beschreibung:
The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11328R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11328R-CY3
Lokale Artikelnummer::
BOSSBS-11328R-CY3
Beschreibung:
The brain-specific STEP (striatal enriched phosphatase) family of protein tyrosine phosphatases (PTPs) comprises both transmembrane and cytosolic protein members which are the products of alternative splicing. STEP family members are expressed in the dopaminoceptive neurons of the CNS, with highest expression in the basal ganglia and related structures. The STEP protein regulates the N-methyl-d-aspartate receptor (NMDAR) complex; STEP depresses both NMDAR single-channel activity and synaptic currents. The membrane-associated STEP61 isoform localizes in the postsynaptic densities (PSDs) of striatal neurons. STEP61 contains a single tyrosine phosphatase domain, two proline-rich domains and two transmembrane domains. The STEP61 protein associates with the Src family kinase member Fyn when Fyn is phosphorylated at Tyr-420 and not Tyr-431. Upon association, STEP61 dephosphorylates Tyr-420 residue and may thus regulate Fyn activity in PSDs. Isolated from mouse brain, the STEP20 isoform lacks the conserved tyrosine phosphatase domain. The human STEP gene maps to chromosome 11p15.2-p15.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1851R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1851R-CY5
Lokale Artikelnummer::
BOSSBS-1851R-CY5
Beschreibung:
Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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