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17-DMAG+hydrochloride
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17-DMAG+hydrochloride
Artikel-Nr:
(BOSSBS-9366R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9366R-A680
Lokale Artikelnummer::
BOSSBS-9366R-A680
Beschreibung:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9366R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9366R-FITC
Lokale Artikelnummer::
BOSSBS-9366R-FITC
Beschreibung:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD10694-10G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD10694-10G
Lokale Artikelnummer::
BLDPBD10694-10G
Beschreibung:
3,5-Dimethylphenylhydraziniumchlorid 95%
VE:
1 * 10 g
Artikel-Nr:
(BOSSBS-3451R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-CY3
Lokale Artikelnummer::
BOSSBS-3451R-CY3
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13606R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13606R-A680
Lokale Artikelnummer::
BOSSBS-13606R-A680
Beschreibung:
Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NF_B expression, thereby inhibiting NF_B-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12180R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12180R-CY7
Lokale Artikelnummer::
BOSSBS-12180R-CY7
Beschreibung:
The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5285R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5285R-A647
Lokale Artikelnummer::
BOSSBS-5285R-A647
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
3,5-Dichlorphenylhydraziniumchlorid ≥97%
Lieferant:
Alfa Aesar
Beschreibung:
2,6-Dichlorphenylhydraziniumchlorid ≥98%
Artikel-Nr:
(BOSSBS-11695R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11695R-A680
Lokale Artikelnummer::
BOSSBS-11695R-A680
Beschreibung:
The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe²⁺ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
3-Fluorphenylhydraziniumchlorid ≥98%
Artikel-Nr:
(A18358.14)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
A18358.14
Lokale Artikelnummer::
ALFAA18358.14
Beschreibung:
Ethyl-L-tyrosinathydrochlorid 99%
VE:
1 * 25 g
Lieferant:
VWR Chemicals
Beschreibung:
Hydroxylammoniumchlorid ≥99,0%, AnalaR NORMAPUR® Reag. Ph. Eur. analytisches Reagens
Lieferant:
Alfa Aesar
Beschreibung:
3-Chlorphenylhydraziniumchlorid ≥97%
Lieferant:
Thermo Scientific
Beschreibung:
Methylammoniumchlorid 99%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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