17-DMAG+hydrochloride
Artikel-Nr:
(BOSSBS-6592R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6592R-CY5.5
Lokale Artikelnummer::
BOSSBS-6592R-CY5.5
Beschreibung:
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.Tissue specificity; Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.Sequence similarities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD206188-10G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD206188-10G
Lokale Artikelnummer::
BLDPBD206188-10G
Beschreibung:
(2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride 96%
VE:
1 * 10 g
Artikel-Nr:
(APOSOR2766-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR2766-1G
Lokale Artikelnummer::
APOSOR2766-1G
Beschreibung:
3-[(Dimethylamino)methyl]benzeneboronic acid, pinacol ester hydrochloride
VE:
1 * 1 g
Artikel-Nr:
(APOSOR17129-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR17129-1G
Lokale Artikelnummer::
APOSOR17129-1G
Beschreibung:
(3R)-3-Methylmorpholinhydrochlorid 97%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-(4-(Trifluoromethyl)phenyl)propan-2-amine hydrochloride 97%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(Prop-2-yn-1-yl)pyrrolidine hydrochloride 95%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Chloro-6-iodopyridine-2,3-diamine hydrochloride 95%
Artikel-Nr:
(APOSOR33629-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR33629-1G
Lokale Artikelnummer::
APOSOR33629-1G
Beschreibung:
3-Amino-1,2,3,4-tetrahydroquinolin-2-one hydrochloride 95%
VE:
1 * 1 g
Artikel-Nr:
(APOSOR932821-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR932821-1G
Lokale Artikelnummer::
APOSOR932821-1G
Beschreibung:
6,7-Dihydroisoquinolin-8(5H)-one hydrochloride 95%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-(Aminomethyl)phenylboronic acid pinacol ester hydrochloride
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-[Amino-(4-bromo-phenyl)-methyl]-naphthalen-2-ol hydrochloride
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-(Methylsulfonyl)ethanaminhydrochlorid
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Methyl-2-amino-4-(2-methoxy-2-oxoethyl)thiazole-5-carboxylate hydrochloride 95+%
Artikel-Nr:
(APOSOR70192-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR70192-100G
Lokale Artikelnummer::
APOSOR70192-100G
Beschreibung:
(3S)-3-Methylpiperazine hydrochloride, N1-BOC protected
VE:
1 * 100 g
Lieferant:
Biotium
Beschreibung:
This MAb recognizes human 17-26 kDa protein, which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha). TNF-alpha can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
Lieferant:
Biotium
Beschreibung:
This MAb recognizes human 17-26 kDa protein, which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha). TNF-alpha can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
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