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4-Chloro-2-methylbenzofuro[3,2-d]pyrimidine
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4-Chloro-2-methylbenzofuro[3,2-d]pyrimidine
Artikel-Nr:
(BOSSBS-11552R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11552R-A350
Lokale Artikelnummer::
BOSSBS-11552R-A350
Beschreibung:
The engrailed-2 gene, EN2, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homologs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expression of a-synuclein, a gene that is genetically linked to Parkinson’s disease. During early brain development mouse EN-2 is expressed in a broad band across most of the mid-hindbrain region. EN-2 is also expressed in mouse myoblasts and has been assiciated with cerebellar hypoplasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11552R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11552R-CY5
Lokale Artikelnummer::
BOSSBS-11552R-CY5
Beschreibung:
The engrailed-2 gene, EN2, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homologs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expression of a-synuclein, a gene that is genetically linked to Parkinson’s disease. During early brain development mouse EN-2 is expressed in a broad band across most of the mid-hindbrain region. EN-2 is also expressed in mouse myoblasts and has been assiciated with cerebellar hypoplasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11827R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11827R-CY3
Lokale Artikelnummer::
BOSSBS-11827R-CY3
Beschreibung:
DRGX is a transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11128R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11128R-CY5
Lokale Artikelnummer::
BOSSBS-11128R-CY5
Beschreibung:
Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13681R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13681R-CY5
Lokale Artikelnummer::
BOSSBS-13681R-CY5
Beschreibung:
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4062R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4062R-CY3
Lokale Artikelnummer::
BOSSBS-4062R-CY3
Beschreibung:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4062R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4062R-CY5.5
Lokale Artikelnummer::
BOSSBS-4062R-CY5.5
Beschreibung:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4062R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4062R
Lokale Artikelnummer::
BOSSBS-4062R
Beschreibung:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4212R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4212R-A680
Lokale Artikelnummer::
BOSSBS-4212R-A680
Beschreibung:
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2686R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2686R-A750
Lokale Artikelnummer::
BOSSBS-2686R-A750
Beschreibung:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4212R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4212R-HRP
Lokale Artikelnummer::
BOSSBS-4212R-HRP
Beschreibung:
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2162R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2162R-FITC
Lokale Artikelnummer::
BOSSBS-2162R-FITC
Beschreibung:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2686R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2686R-HRP
Lokale Artikelnummer::
BOSSBS-2686R-HRP
Beschreibung:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6388R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6388R-CY5
Lokale Artikelnummer::
BOSSBS-6388R-CY5
Beschreibung:
This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5675R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5675R-A488
Lokale Artikelnummer::
BOSSBS-5675R-A488
Beschreibung:
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5675R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5675R-A647
Lokale Artikelnummer::
BOSSBS-5675R-A647
Beschreibung:
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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