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[cis-3-Methoxycyclobutyl]methanamine+hydrochloride
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[cis-3-Methoxycyclobutyl]methanamine+hydrochloride
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Artikel-Nr:
(BOSSBS-10490R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10490R
Lokale Artikelnummer::
BOSSBS-10490R
Beschreibung:
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Artikel-Nr:
(BOSSBS-10421R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10421R-A680
Lokale Artikelnummer::
BOSSBS-10421R-A680
Beschreibung:
Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells. It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin Signalling pathway and the phosphorylation and destruction of the MYB transcription factor. It may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (referenced from swissprot).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5986R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5986R-CY5
Lokale Artikelnummer::
BOSSBS-5986R-CY5
Beschreibung:
Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1699R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1699R-CY7
Lokale Artikelnummer::
BOSSBS-1699R-CY7
Beschreibung:
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin 9 is an S-type lectin and an eosinophil chemoattractant (ECA) produced by antigen-activated T cells. Galectin 9 is involved in apoptosis, is thought to be a prognostic factor for breast cancer and is also overexpressed in Hodgkin's disease tissue. The protein has N- and C- terminal carbohydrate-binding domains connected by a link peptide. Multiple alternatively spliced transcript variants have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7626R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7626R
Lokale Artikelnummer::
BOSSBS-7626R
Beschreibung:
RelevanceHAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7626R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7626R-CY5.5
Lokale Artikelnummer::
BOSSBS-7626R-CY5.5
Beschreibung:
RelevanceHAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7626R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7626R-CY5
Lokale Artikelnummer::
BOSSBS-7626R-CY5
Beschreibung:
RelevanceHAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2454R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2454R-A488
Lokale Artikelnummer::
BOSSBS-2454R-A488
Beschreibung:
Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2454R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2454R-FITC
Lokale Artikelnummer::
BOSSBS-2454R-FITC
Beschreibung:
Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3724R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3724R-HRP
Lokale Artikelnummer::
BOSSBS-3724R-HRP
Beschreibung:
This gene encodes one of three opioid receptors. The mu opioid receptor is the principal target of endogenous opioid peptides and opioid analgesic agents such a s beta-endorphn and enkephalins. The NM_001008503.1:c.118A>G allele had been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5015R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5015R-A647
Lokale Artikelnummer::
BOSSBS-5015R-A647
Beschreibung:
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Artikel-Nr:
(BOSSBS-3299R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3299R-FITC
Lokale Artikelnummer::
BOSSBS-3299R-FITC
Beschreibung:
E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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