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[(tert-Butoxycarbonyl)aminooxy]acetic+acid
Lieferant:
Biotium
Beschreibung:
This MAb reacts with the HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. It binds a conformational epitope on HLA-DR, which depends on the correct folding of the α/β heterodimer. This MAb has been reported to block mixed lymphocyte reactions. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kD alpha (heavy) chain and a 28kD beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Artikel-Nr:
(BOSSBS-8444R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8444R-CY7
Lokale Artikelnummer::
BOSSBS-8444R-CY7
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
Collagenases degrade native helical collagen fibrils. The enzyme has an important role in connective tissue metabolism and is produced by specific cells involved in repairs and remodelling processes. It is a type II enzyme that contains greater clostripain activity. It is generally used for heart, bone, muscle, thyroid, cartilage, and liver cells. Ca²⁺ is required for its activation while metal chelating agents such as cysteine, EDTA or o-phenanthroline inhibits its activity.
Artikel-Nr:
(BARNCV703X4A)
Lieferant:
BARNSTEAD THERMOLYNE
Hersteller-Artikelnummer::
CV703X4A
Lokale Artikelnummer::
BARNCV703X4A
Beschreibung:
Behälterverschluss, Für: Ultrareine Wassersysteme, Barnstead EasyPure® II
VE:
1 * 1 ST
Artikel-Nr:
(MOLE33858797-5G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
33858797-5G
Lokale Artikelnummer::
MOLE33858797-5G
Beschreibung:
Bariumtrifluormethansulfonat
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
Texwipe
Beschreibung:
Diese Wischtücher bestehen aus einer wasserstrahlverfestigten Vliesmischung aus 55% Cellulose und 45% Polyester. Dieses Mischfasergewebe vereint die extrem hohe Saugfähigkeit von Naturfasern mit der Reinheit und Festigkeit von synthetischem Material. Die TechniCloth® II Tücher sind dank einzigartiger Technologie äußerst partikelarm und damit noch partikelärmer als die TechniCloth® Tücher.
Artikel-Nr:
(BOSSBS-8444R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8444R-A350
Lokale Artikelnummer::
BOSSBS-8444R-A350
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11180R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11180R-A647
Lokale Artikelnummer::
BOSSBS-11180R-A647
Beschreibung:
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5221R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5221R-A350
Lokale Artikelnummer::
BOSSBS-5221R-A350
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11180R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11180R-CY3
Lokale Artikelnummer::
BOSSBS-11180R-CY3
Beschreibung:
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8444R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8444R-A488
Lokale Artikelnummer::
BOSSBS-8444R-A488
Beschreibung:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
VE:
1 * 100 µl
Artikel-Nr:
(USBI134872)
Lieferant:
US Biological
Hersteller-Artikelnummer::
134872
Lokale Artikelnummer::
USBI134872
Beschreibung:
Anti-TDP2 Mouse Polyclonal Antibody
VE:
1 * 50 µG
Lieferant:
Alfa Aesar
Beschreibung:
Calciumsulfat, Drierite™ 3 mm (8 mesh) für die Trocknung, mit Indikator (Kobalt (II) Chlorid)
Lieferant:
Alfa Aesar
Beschreibung:
Zinksulfat Heptahydrat 99,0-103,0% ACS
Lieferant:
Agilent
Beschreibung:
Key design features of nebulisers for PerkinElmer ICP-MS systems provide the best precision, efficient drainage, minimal burner blockage, and reduced interferences.
Artikel-Nr:
(PRSI33-732)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-732
Lokale Artikelnummer::
PRSI33-732
Beschreibung:
This mAb reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some auto-immune diseases are associated with certain class II alleles.
VE:
1 * 100 µG
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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