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4,4\\\\\\\'-Methylenebis(2-methylcyclohexylamine)+(mixture+of+iso
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4,4\\\\\\\'-Methylenebis(2-methylcyclohexylamine)+(mixture+of+iso
Lieferant:
Alfa Aesar
Beschreibung:
4-Nitrophenylhydrazine mono and dihydrochloride exhibits potential anticancer activity. It acts as a derivatizing agent for carbonyl compounds. It is also used as pharmaceutical intermediates.
Lieferant:
G-Biosciences
Beschreibung:
A selection of strong chemicals to aid in the denaturation of proteins. Denaturants, or chaotropes, disrupt water interactions resulting in the solubilization of hydrophobic proteins and peptides. The chaotropes also act on all proteins to unfold them and alter their three-dimensional structure.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Fluorphenylhydraziniumchlorid 98%
Artikel-Nr:
(BOSSBS-3935R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3935R-A350
Lokale Artikelnummer::
BOSSBS-3935R-A350
Beschreibung:
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq].
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
USP, Pyrogen free
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2,4-Dimethylphenylhydraziniumchlorid 97%
Lieferant:
Alfa Aesar
Beschreibung:
4-Fluorphenylhydraziniumchlorid ≥98%
Artikel-Nr:
(BLDPBD10694-10G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD10694-10G
Lokale Artikelnummer::
BLDPBD10694-10G
Beschreibung:
3,5-Dimethylphenylhydraziniumchlorid 95%
VE:
1 * 10 g
Artikel-Nr:
(BOSSBS-4197R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4197R-FITC
Lokale Artikelnummer::
BOSSBS-4197R-FITC
Beschreibung:
The Sarco(endo)plasmic-reticulum (SER) regulatory protein, Phospholamban (PLB), is a small, plasma membrane-associated protein found in the SER of cardiac, smooth and slow-twitch muscle. Believed to assemble into a pentamer, PLB regulates cardiac contractility and Ca2+ affinity for cardiac SER Ca2+ ATPase (SERCA2a). Non-phosphorylated PLB associates with SERCA2a, and inhibits Ca2+ reuptake into the SER. PLB activation occurs when key Serine/Threonine residues in PLB (Ser-10, Ser-16, Thr-17) are phosphorylated by numerous effectors, which include PKC, PKA, PKG, and CaM kinase. Phosphorylation of PLB causes dissociation from SERCA2a and a subsequent increase in the rate of Ca2+ reuptake into the SER, which accelerates ventricular relaxation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9366R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9366R-CY7
Lokale Artikelnummer::
BOSSBS-9366R-CY7
Beschreibung:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9366R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9366R-A680
Lokale Artikelnummer::
BOSSBS-9366R-A680
Beschreibung:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9366R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9366R-FITC
Lokale Artikelnummer::
BOSSBS-9366R-FITC
Beschreibung:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5285R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5285R-A647
Lokale Artikelnummer::
BOSSBS-5285R-A647
Beschreibung:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3451R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-CY3
Lokale Artikelnummer::
BOSSBS-3451R-CY3
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13606R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13606R-A680
Lokale Artikelnummer::
BOSSBS-13606R-A680
Beschreibung:
Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NF_B expression, thereby inhibiting NF_B-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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