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3-(Chlorsulfonyl)benzoesäure
Artikel-Nr:
(BOSSBS-5337R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5337R-CY5
Lokale Artikelnummer::
BOSSBS-5337R-CY5
Beschreibung:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7780R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7780R-CY7
Lokale Artikelnummer::
BOSSBS-7780R-CY7
Beschreibung:
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3018R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3018R-CY5
Lokale Artikelnummer::
BOSSBS-3018R-CY5
Beschreibung:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3019R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3019R-CY3
Lokale Artikelnummer::
BOSSBS-3019R-CY3
Beschreibung:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15497R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15497R-CY7
Lokale Artikelnummer::
BOSSBS-15497R-CY7
Beschreibung:
DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15088R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15088R-A350
Lokale Artikelnummer::
BOSSBS-15088R-A350
Beschreibung:
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3501R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3501R-A555
Lokale Artikelnummer::
BOSSBS-3501R-A555
Beschreibung:
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15088R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15088R-HRP
Lokale Artikelnummer::
BOSSBS-15088R-HRP
Beschreibung:
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9668R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9668R-A750
Lokale Artikelnummer::
BOSSBS-9668R-A750
Beschreibung:
Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8376R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8376R-FITC
Lokale Artikelnummer::
BOSSBS-8376R-FITC
Beschreibung:
RNF160 may function as an E3 ubiquitin-protein ligase. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12942R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12942R-A750
Lokale Artikelnummer::
BOSSBS-12942R-A750
Beschreibung:
All members of the Src gene family of tyrosine kinases are characterised by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5 to 10 fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3451R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-A350
Lokale Artikelnummer::
BOSSBS-3451R-A350
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13087R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13087R-HRP
Lokale Artikelnummer::
BOSSBS-13087R-HRP
Beschreibung:
The erythropoietin receptor (EPOR) is a member of the cytokine receptor family. There are several isoforms including: EPOR-F (full length), EPOR-S (soluble form), and EPOR-T (truncated form). Upon erythropoietin (EPO) binding, the EPOR activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated EPOR appears to have a role in erythroid cell survival. Defects in the EPOR may produce erythroleukemia and familial erythrocytosis. A functional EPOR is found in the cardiovascular system, including endothelial cells and cardiomyocytes, and data suggest that the EPO/EPO receptor system plays an important role in cardiac function. In animal studies, treatment with EPO during ischemia/reperfusion in the heart has been shown to limit the infarct size and the extent of apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3451R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-A488
Lokale Artikelnummer::
BOSSBS-3451R-A488
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12141R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12141R-A647
Lokale Artikelnummer::
BOSSBS-12141R-A647
Beschreibung:
LRFN1 is a 771 amino acid single-pass type I membrane protein that belongs to the LRFN family. Containing a fibronectin type-III domain, an Ig-like (immunoglobulin-like) domain, a LRRCT domain, a LRRNT domain and seven LRR (leucine-rich) repeats, LRFN1 is thought to promote neurite outgrowth in hippocampal neurons and is involved in the regulation and maintenance of excitatory synapses. LRFN1 forms heteromeric complexes with LRFN2, LRFN3, LFRN4 and LFRN5, but does not have the ability to form homomeric complexes across cell junctions of adjacent cells like other LRFN family members. The PDZ-binding motif of LRFN1 is required for neurite outgrowth promotion and for SAP 97-, NE-dlg- and PSD-95-binding. LRFN1 is encoded by a gene located on human chromosome 19q13.2 and mouse chromosome 7 A3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3451R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3451R-HRP
Lokale Artikelnummer::
BOSSBS-3451R-HRP
Beschreibung:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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