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2-(4-Isobutylphenyl)acetic+acid
Artikel-Nr:
(USBIT2040-02W2)
Lieferant:
US Biological
Hersteller-Artikelnummer::
T2040-02W2
Lokale Artikelnummer::
USBIT2040-02W2
Beschreibung:
Anti-TCR, alpha, beta, V beta 2 Mouse Monoclonal Antibody (Biotin) [clone: 5K83]
VE:
1 * 500 µG
Lieferant:
VWR Chemicals
Beschreibung:
IPTG (Isopropyl-β-D-thiogalactopyranosid) ≥99,0%, Ultrareine Qualität
Artikel-Nr:
(ORIGTA130050)
Lieferant:
OriGene
Hersteller-Artikelnummer::
TA130050
Lokale Artikelnummer::
ORIGTA130050
Beschreibung:
Anti-IgG Rabbit gamma Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 1 mg
Artikel-Nr:
(ORIGTA130004)
Lieferant:
OriGene
Hersteller-Artikelnummer::
TA130004
Lokale Artikelnummer::
ORIGTA130004
Beschreibung:
Anti-IgG Goat gamma Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 0,5 mg
Artikel-Nr:
(ORIGTA130023)
Lieferant:
OriGene
Hersteller-Artikelnummer::
TA130023
Lokale Artikelnummer::
ORIGTA130023
Beschreibung:
Anti-IgG Goat gamma Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 0,5 mg
Artikel-Nr:
(ORIGTA130005)
Lieferant:
OriGene
Hersteller-Artikelnummer::
TA130005
Lokale Artikelnummer::
ORIGTA130005
Beschreibung:
Anti-IgG Goat gamma Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 1 mg
Artikel-Nr:
(BOSSBS-12943R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12943R-HRP
Lokale Artikelnummer::
BOSSBS-12943R-HRP
Beschreibung:
Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase I Alpha, I Gamma, I Delta and I Epsilon, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Casein kinase I isoform alpha-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the alpha isoform of casein kinase 1. CSNK1A1L resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, CSNK1A1L phosphorylates a large number of proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2374R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2374R-A750
Lokale Artikelnummer::
BOSSBS-2374R-A750
Beschreibung:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5564R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5564R-CY3
Lokale Artikelnummer::
BOSSBS-5564R-CY3
Beschreibung:
Protein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2374R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2374R-CY7
Lokale Artikelnummer::
BOSSBS-2374R-CY7
Beschreibung:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Artikel-Nr:
(BOSSBS-6428R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6428R-CY7
Lokale Artikelnummer::
BOSSBS-6428R-CY7
Beschreibung:
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2374R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2374R-CY3
Lokale Artikelnummer::
BOSSBS-2374R-CY3
Beschreibung:
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0490R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0490R-A750
Lokale Artikelnummer::
BOSSBS-0490R-A750
Beschreibung:
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-14 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyses RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6428R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6428R-FITC
Lokale Artikelnummer::
BOSSBS-6428R-FITC
Beschreibung:
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Goat anti-human IgG, Fc gamma specific antibody reacts specifically with the human IgG heavy (γ) chains and not with light chains and F(ab’)2 fragment on all human immunoglobulins. To minimize cross-reactivity, it has been adsorbed against bovine, horse, mouse and rabbit serum proteins prior to conjugation. CF™594 (Ex/Em 593/614 nm) is a deep-red dye spectrally similar to Alexa Fluor® 594 and Texas Red® dye but yields much brighter protein conjugates due to its high quantum yield and exceptional water solubility. CF™594 also has excellent photostability ideal for demanding applications, such as confocal microscopy and single molecule imaging.
Alexa Fluor® and Texas Red® are registered trademarks of Thermo Fisher Scientific.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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