Bis(4-tert-butylphenyl)iodonium-p-toluenesulphonate
Artikel-Nr:
(BOSSBS-13267R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13267R-CY7
Lokale Artikelnummer::
BOSSBS-13267R-CY7
Beschreibung:
GALK2 is important in the first step of the galactose metabolism pathway. GALK1, which belongs to the GHMP kinase family of proteins, is a crucial enzyme for galactose metabolism, specifically converting ?d-galactose to galactose 1-phosphate. Defects in the gene encoding GALK1 can cause galactosemia II, an autosomal recessive disorder characterized by congenital cataracts during infancy, often within the first two weeks of life. In the adult population, galactosemia II can cause presenile cataracts that are secondary to accumulation of galactitol in the lens of the eye. A second gene, GALK2, encodes an enzyme with greater activity against GalNAc than galactose. GALK2 has been implicated in the salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.This MAb was characterized as human CD4 antibody at II and IV International Workshop on Human Leukocyte Differentiation Antigens.
Artikel-Nr:
(BOSSBS-12416R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12416R-A350
Lokale Artikelnummer::
BOSSBS-12416R-A350
Beschreibung:
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0051R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0051R-A488
Lokale Artikelnummer::
BOSSBS-0051R-A488
Beschreibung:
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6650R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6650R-CY5.5
Lokale Artikelnummer::
BOSSBS-6650R-CY5.5
Beschreibung:
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6650R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6650R-HRP
Lokale Artikelnummer::
BOSSBS-6650R-HRP
Beschreibung:
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0051R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0051R-A647
Lokale Artikelnummer::
BOSSBS-0051R-A647
Beschreibung:
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6650R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6650R-A488
Lokale Artikelnummer::
BOSSBS-6650R-A488
Beschreibung:
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Artikel-Nr:
(USBID3714-20A-BIOT)
Lieferant:
US Biological
Hersteller-Artikelnummer::
D3714-20A-BIOT
Lokale Artikelnummer::
USBID3714-20A-BIOT
Beschreibung:
Anti-DIO2 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-8671R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8671R-A680
Lokale Artikelnummer::
BOSSBS-8671R-A680
Beschreibung:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3970R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3970R-CY3
Lokale Artikelnummer::
BOSSBS-3970R-CY3
Beschreibung:
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1873R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1873R-CY3
Lokale Artikelnummer::
BOSSBS-1873R-CY3
Beschreibung:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2097R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2097R-A680
Lokale Artikelnummer::
BOSSBS-2097R-A680
Beschreibung:
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Bariumfluorid ≥99,99% (Metall-Basis), Puratronic®
Artikel-Nr:
(ABCAAB168782-50)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB168782-50
Lokale Artikelnummer::
ABCAAB168782-50
Beschreibung:
Anti-DNASE2 Mouse Polyclonal Antibody
VE:
1 * 50 µG
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Artikel-Nr:
(BOSSBS-12347R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12347R-FITC
Lokale Artikelnummer::
BOSSBS-12347R-FITC
Beschreibung:
Affected males of X-linked anhidrotic ectodermal dysplasia show hypotrichosis, abnormal teeth and absent sweat glands. Some of the patients reported by Halperin and Curtis showed mental defect also, but this is not an invariable feature. Ectodysplasin A (EDA) is a trimeric type II membrane protein that co-localizes with cytoskeletal structures at the lateral and apical surfaces of cells. EDA is expressed in hair follicles and in the epidermis of adult skin. The sequence of the longest isoform includes an interrupted collagenous domain of 19 Gly-X-Y repeats and a motif conserved in the tumor necrosis factor (TNF)-related ligand family. EDA is a member of the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation. Similar to other members of collagenous membrane proteins and members of TNF-related ligands, EDA is a type II membrane protein which forms trimers.
VE:
1 * 100 µl
Preis auf Anfrage
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