2-Methyl-3-pyridinboronsäure+Hydrochlorid
Lieferant:
Thermo Scientific
Beschreibung:
Ethyl-N-hydroxyacetimidat 97%
Lieferant:
Biotium
Beschreibung:
This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
Artikel-Nr:
(BOSSBS-11028R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11028R-CY5
Lokale Artikelnummer::
BOSSBS-11028R-CY5
Beschreibung:
Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD248397-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD248397-5G
Lokale Artikelnummer::
BLDPBD248397-5G
Beschreibung:
N-Ethyl-4-chlorobenzylamine 98%
VE:
1 * 5 g
Lieferant:
Alfa Aesar
Beschreibung:
Ethyl-4-nitrobenzoat ≥98%
Artikel-Nr:
(93103-5MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
93103-5MG
Lokale Artikelnummer::
SUPL93103-5MG
Beschreibung:
Organic Standard, Paraoxon-ethyl-d10 (diethyl-d₁₀)
VE:
1 * 5 mg
Artikel-Nr:
(BOSSBS-8299R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8299R-CY3
Lokale Artikelnummer::
BOSSBS-8299R-CY3
Beschreibung:
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8299R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8299R-CY5
Lokale Artikelnummer::
BOSSBS-8299R-CY5
Beschreibung:
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1091R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1091R-CY7
Lokale Artikelnummer::
BOSSBS-1091R-CY7
Beschreibung:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4251R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4251R-CY3
Lokale Artikelnummer::
BOSSBS-4251R-CY3
Beschreibung:
PHD1 catalyzes the posttranslational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins and hydroxylates HIF-1 alpha at Pro-402 and Pro-564, and HIF-2 alpha. It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex. It may play a role in cell growth regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8546R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8546R-FITC
Lokale Artikelnummer::
BOSSBS-8546R-FITC
Beschreibung:
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8546R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8546R-A350
Lokale Artikelnummer::
BOSSBS-8546R-A350
Beschreibung:
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity (By similarity). Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR309214-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR309214-1G
Lokale Artikelnummer::
APOSOR309214-1G
Beschreibung:
6-Ethyl-4-hydroxyquinoline
VE:
1 * 1 g
Artikel-Nr:
(APOSOR110955-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR110955-25G
Lokale Artikelnummer::
APOSOR110955-25G
Beschreibung:
Ethyl-6-hydroxynicotinate 95%
VE:
1 * 25 g
Lieferant:
Biotium
Beschreibung:
Granulocyte/macrophage - Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.
Lieferant:
Biotium
Beschreibung:
Granulocyte/macrophage - Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.
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