2-Amino-5-bromo-4-methoxybenzoic+acid
Artikel-Nr:
(BOSSBS-8436R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8436R-A750
Lokale Artikelnummer::
BOSSBS-8436R-A750
Beschreibung:
BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0202R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0202R-A488
Lokale Artikelnummer::
BOSSBS-0202R-A488
Beschreibung:
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9372R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9372R-CY5.5
Lokale Artikelnummer::
BOSSBS-9372R-CY5.5
Beschreibung:
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8586R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8586R-CY7
Lokale Artikelnummer::
BOSSBS-8586R-CY7
Beschreibung:
GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15483R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15483R-CY3
Lokale Artikelnummer::
BOSSBS-15483R-CY3
Beschreibung:
HIBADH is a 336 amino acid mitochondrial enzyme that catalyses the NAD+-dependent, reversible oxidisation of 3-Hydroxyisobutyrate to methylmalonate semialdehyde, an intermediate of valine catabolism. The enzyme functions as a homodimer between a pH of 7,0 and 10,0, with optimal activity between 8,8 and 9,0. It was previously hypothesised that defects in the gene encoding HIBADH may be the cause of 3-Hydroxyisobutyric aciduria, a rare disorder that is characterised by a variety of clinical manifestations such as neurodevelopmental problems and dysmorphic features. However, it was shown that HIBADH activity was equal in patients with 3-Hydroxyisobutyric aciduria as compared with controls.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12423R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12423R-A488
Lokale Artikelnummer::
BOSSBS-12423R-A488
Beschreibung:
Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic β-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Amino-4-oxazolcarbonsäure
Artikel-Nr:
(BOSSBS-15420R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15420R-A680
Lokale Artikelnummer::
BOSSBS-15420R-A680
Beschreibung:
HBS1L is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and _-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0202R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0202R-HRP
Lokale Artikelnummer::
BOSSBS-0202R-HRP
Beschreibung:
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11497R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11497R-A680
Lokale Artikelnummer::
BOSSBS-11497R-A680
Beschreibung:
VAX2 is a 290 amino acid homeobox protein that plays a crucial role in development of the eye, particularly in the specification of the ventral optic vesicle and in establishment of a correct dorsoventral pattern. VAX2 acts as a transcription factor with VAX1 to cooperatively regulate retinal differentiation, neuroepithelial cell proliferation and axial polarisation in the retina. Together, VAX1 and VAX2 repress transcription of Pax-6, a strong inducer of retinal development. VAX1 and VAX2 localize to the nucleus and contain one homeobox DNA-binding domain each.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15420R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15420R-HRP
Lokale Artikelnummer::
BOSSBS-15420R-HRP
Beschreibung:
HBS1L is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and _-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0932R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0932R-A750
Lokale Artikelnummer::
BOSSBS-0932R-A750
Beschreibung:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12423R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12423R-A350
Lokale Artikelnummer::
BOSSBS-12423R-A350
Beschreibung:
Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic β-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13613R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13613R-CY3
Lokale Artikelnummer::
BOSSBS-13613R-CY3
Beschreibung:
The leucine-rich repeat-containing protein 6 (LRRC6), also designated Leucine-rich testis-specific protein (LRTP), is a 466 amino acid protein that contains 3 LRR repeats and plays a role in spermatogenesis. The gene encoding LRRC6 maps to chromosome 8, which encodes approximately 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Chromosome 8 is also associated with Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9662R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9662R
Lokale Artikelnummer::
BOSSBS-9662R
Beschreibung:
EFR3A is a plasma membrane protein that contains 821 amino acids and belongs to the EFR3 family. EFR3A is alternatively spliced creating three isoforms and is encoded by a gene that maps to human chromosome 8. Human chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8586R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8586R-A488
Lokale Artikelnummer::
BOSSBS-8586R-A488
Beschreibung:
GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
VE:
1 * 100 µl
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