Pyrazine-2-carboxylic+acid
Artikel-Nr:
(BOSSBS-8165R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8165R-A488
Lokale Artikelnummer::
BOSSBS-8165R-A488
Beschreibung:
Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12143R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12143R-CY7
Lokale Artikelnummer::
BOSSBS-12143R-CY7
Beschreibung:
Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters. By way of this control of actin dynamics, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling. Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity. May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8998R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8998R-A750
Lokale Artikelnummer::
BOSSBS-8998R-A750
Beschreibung:
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13067R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13067R-FITC
Lokale Artikelnummer::
BOSSBS-13067R-FITC
Beschreibung:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR60171-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR60171-1G
Lokale Artikelnummer::
APOSOR60171-1G
Beschreibung:
2-Ethyl-5-nitrobenzoxazol
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-N-hydroxyacetimidat 96%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-2-oxocyclohexancarboxylat 95%
Artikel-Nr:
(BLDPBD5080-500G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD5080-500G
Lokale Artikelnummer::
BLDPBD5080-500G
Beschreibung:
Ethyl-1-cyanocyclopropanecarboxylate 97%
VE:
1 * 500 g
Lieferant:
Alfa Aesar
Beschreibung:
Ethyl Rot
Lieferant:
Thermo Scientific
Beschreibung:
Ethyl-4-fluorbenzoat 99%
Artikel-Nr:
(H32931.06)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
H32931.06
Lokale Artikelnummer::
ALFAH32931.06
Beschreibung:
Ethyl-2-fluoroisobutyrate 97%
VE:
1 * 5 g
Lieferant:
Alfa Aesar
Beschreibung:
Ethyl α-bromphenylacetat ≥97%
Lieferant:
Alfa Aesar
Beschreibung:
Ethyl-5-bromnicotinat ≥98%
Artikel-Nr:
(APOSOR310644-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR310644-5G
Lokale Artikelnummer::
APOSOR310644-5G
Beschreibung:
Ethyl-2-cyclohexanoneacetate
VE:
1 * 5 g
Preis auf Anfrage
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