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2-Aminobenzo[d]thiazole-6-carboxylic+acid
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2-Aminobenzo[d]thiazole-6-carboxylic+acid
Artikel-Nr:
(BOSSBS-1322R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1322R-FITC
Lokale Artikelnummer::
BOSSBS-1322R-FITC
Beschreibung:
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1927R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1927R-HRP
Lokale Artikelnummer::
BOSSBS-1927R-HRP
Beschreibung:
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6473R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6473R-FITC
Lokale Artikelnummer::
BOSSBS-6473R-FITC
Beschreibung:
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362). Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression. Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4259R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4259R-A647
Lokale Artikelnummer::
BOSSBS-4259R-A647
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4259R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4259R-FITC
Lokale Artikelnummer::
BOSSBS-4259R-FITC
Beschreibung:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7949R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7949R-A750
Lokale Artikelnummer::
BOSSBS-7949R-A750
Beschreibung:
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
VE:
1 * 100 µl
Artikel-Nr:
(NALG6219-0068)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
6219-0068
Lokale Artikelnummer::
NALG6219-0068
Beschreibung:
LDPE. Moulded in one piece. Non wetting material, tapered tip, and bellows-type bulb provide excellent drop formation.
VE:
1 * 100 ST
Artikel-Nr:
(BOSSBS-11317R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11317R-A750
Lokale Artikelnummer::
BOSSBS-11317R-A750
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11317R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11317R-A350
Lokale Artikelnummer::
BOSSBS-11317R-A350
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10233R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10233R-A647
Lokale Artikelnummer::
BOSSBS-10233R-A647
Beschreibung:
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11317R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11317R-A647
Lokale Artikelnummer::
BOSSBS-11317R-A647
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4159R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4159R-CY3
Lokale Artikelnummer::
BOSSBS-4159R-CY3
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4159R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4159R-CY5.5
Lokale Artikelnummer::
BOSSBS-4159R-CY5.5
Beschreibung:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5895R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5895R-A647
Lokale Artikelnummer::
BOSSBS-5895R-A647
Beschreibung:
WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases. The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac. They mediate Actin polymerization by cooperating with the Arp2/3 complex, thereby promoting the formation of Actin filaments. WAVE1, which is also designated SCAR (suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes. WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2962R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2962R-HRP
Lokale Artikelnummer::
BOSSBS-2962R-HRP
Beschreibung:
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904). Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein (SU) mediates receptor recognition, while the transmembrane protein (TM) acts as a class I viral fusion protein. The protein may have at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of membranes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15094R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15094R-A488
Lokale Artikelnummer::
BOSSBS-15094R-A488
Beschreibung:
The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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