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2-Brom-4,5-dimethoxybenzoes\u00E4ure
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2-Brom-4,5-dimethoxybenzoes\u00E4ure
Artikel-Nr:
(BOSSBS-13492R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13492R-CY7
Lokale Artikelnummer::
BOSSBS-13492R-CY7
Beschreibung:
The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13492R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13492R-A488
Lokale Artikelnummer::
BOSSBS-13492R-A488
Beschreibung:
The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Brom-tris-pyrrolidinophosphoniumhexafluorophosphat, Sigma-Aldrich®
Lieferant:
FLUOROCHEM
Beschreibung:
2-Amino-4,5-dimethoxybenzonitril
Lieferant:
Sigma-Aldrich
Beschreibung:
4,5-Dimethyl-o-phenylendiamin, Sigma-Aldrich®
Artikel-Nr:
(APOSPC302487-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC302487-1G
Lokale Artikelnummer::
APOSPC302487-1G
Beschreibung:
3-(4-Chloro-3-ethoxy-2-fluorophenyl)propionic acid 97%
VE:
1 * 1 g
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 40-45 kDa, identified as human milk fat globule membrane protein (HMFG). HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 40-45 kDa, identified as human milk fat globule membrane protein (HMFG). HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.
Lieferant:
Biotium
Beschreibung:
This MAb recognizes the 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Lieferant:
Biotium
Beschreibung:
Recognizes a phosphor-protein of 45 kDa, identified as MyoD1. This MAb does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.
Artikel-Nr:
(BOSSBS-8319R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8319R-A350
Lokale Artikelnummer::
BOSSBS-8319R-A350
Beschreibung:
LHPP, also known as HDHD2B, is a 270 amino acid protein that exists as a homodimer and is a member of the HAD-like hydrolase superfamily. Expressed in liver, kidney and moderately in brain, LHPP is encoded by a gene located on 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5134R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5134R-CY5.5
Lokale Artikelnummer::
BOSSBS-5134R-CY5.5
Beschreibung:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0753R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0753R
Lokale Artikelnummer::
BOSSBS-0753R
Beschreibung:
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
2-Hydroxy-4-methoxy-5-sulfobenzophenon Hydrat tech. 85% may cont. up to 10% 2-propanol, technische Qualität
Artikel-Nr:
(BTIUBNUM0245-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0245-50
Lokale Artikelnummer::
BTIUBNUM0245-50
Beschreibung:
Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
VE:
1 * 50 µl
Artikel-Nr:
(COBBHI-1088-5G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
HI-1088-5G
Lokale Artikelnummer::
COBBHI-1088-5G
Beschreibung:
4,5-Dicyan-1-methylimidazol
VE:
1 * 5 g
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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