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4-(tert-Butyl)-2-ethoxybenzoic+acid
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4-(tert-Butyl)-2-ethoxybenzoic+acid
Artikel-Nr:
(BOSSBS-4110R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4110R-A488
Lokale Artikelnummer::
BOSSBS-4110R-A488
Beschreibung:
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Ethyl-4-fluoro-1-nitrobenzene
Artikel-Nr:
(APOSOR110893-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR110893-1G
Lokale Artikelnummer::
APOSOR110893-1G
Beschreibung:
Ethyl 5-bromo-6-hydroxynicotinate
VE:
1 * 1 g
Artikel-Nr:
(APOSOR470492-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR470492-5G
Lokale Artikelnummer::
APOSOR470492-5G
Beschreibung:
Ethyl 3-Bromoindole-1-carboxylate
VE:
1 * 5 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl 2-chloroquinazoline-4-carboxylate
Artikel-Nr:
(BOSSBS-8165R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8165R
Lokale Artikelnummer::
BOSSBS-8165R
Beschreibung:
Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl Quinuclidine-4-carboxylate
Artikel-Nr:
(BOSSBS-5895R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5895R-FITC
Lokale Artikelnummer::
BOSSBS-5895R-FITC
Beschreibung:
WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases. The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac. They mediate Actin polymerization by cooperating with the Arp2/3 complex, thereby promoting the formation of Actin filaments. WAVE1, which is also designated SCAR (suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes. WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5986R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5986R-A488
Lokale Artikelnummer::
BOSSBS-5986R-A488
Beschreibung:
Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
Artikel-Nr:
(BOSSBS-5986R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5986R-FITC
Lokale Artikelnummer::
BOSSBS-5986R-FITC
Beschreibung:
Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Ethyl-3,4,5-trihydroxybenzoat ≥98%
Artikel-Nr:
(BOSSBS-4876R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4876R-A555
Lokale Artikelnummer::
BOSSBS-4876R-A555
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4878R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4878R-A350
Lokale Artikelnummer::
BOSSBS-4878R-A350
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4875R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4875R-A488
Lokale Artikelnummer::
BOSSBS-4875R-A488
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1638R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1638R-A350
Lokale Artikelnummer::
BOSSBS-1638R-A350
Beschreibung:
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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