Suche >
2-(4-Fluorobenzenesulphamido)propanoic+acid
Drucken
Sie suchten nach:
65 442 results were found
2-(4-Fluorobenzenesulphamido)propanoic+acid
Artikel-Nr:
(BOSSBS-13140R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13140R-CY7
Lokale Artikelnummer::
BOSSBS-13140R-CY7
Beschreibung:
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11180R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11180R-FITC
Lokale Artikelnummer::
BOSSBS-11180R-FITC
Beschreibung:
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11180R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11180R-CY7
Lokale Artikelnummer::
BOSSBS-11180R-CY7
Beschreibung:
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1317R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1317R-A555
Lokale Artikelnummer::
BOSSBS-1317R-A555
Beschreibung:
Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
VE:
1 * 100 µl
Artikel-Nr:
(UPCH1452)
Lieferant:
UPCHURCH SCIENTIFIC
Hersteller-Artikelnummer::
1452
Lokale Artikelnummer::
UPCH1452
Beschreibung:
PEEK or FEP.
VE:
1 * 1 ST
Artikel-Nr:
(USBI036361-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
036361-BIOTIN
Lokale Artikelnummer::
USBI036361-BIOTIN
Beschreibung:
Anti-GTF2I Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(SIAL252174-25MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
252174-25MG
Lokale Artikelnummer::
SIAL252174-25MG
Beschreibung:
Zinc meso-tetraphenylporphine ≥94,0% chlorarm, Sigma-Aldrich®
VE:
1 * 25 mg
Artikel-Nr:
(USBI034893-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
034893-BIOTIN
Lokale Artikelnummer::
USBI034893-BIOTIN
Beschreibung:
Anti-EAPII Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Lieferant:
Agilent
Beschreibung:
Z-fold paper, 8,5×11" rolls, for Agilent 3397A, 3396 series II, and 3396A/B/95/94
Lieferant:
Sigma-Aldrich
Beschreibung:
Dinatriumtetrachloropalladat ≥98%, Sigma-Aldrich®
Lieferant:
BIOSEPAR
Beschreibung:
ParasiTrap Eco enthält ein gefülltes Arbeits- und Transportröhrchen I (mit Medium A Eco) und das Arbeitsröhrchen II mit integriertem Filtersystem aus Edelstahl.
Lieferant:
VARIAN
Beschreibung:
Bond Elut™ Certify II was developed specifically for the rapid and effective extraction of acidic drugs and metabolites from urine and other biological matrices. Certify II is a mixed-mode cartridge packed with non-polar C8 and strong anion exchange (SAX) sorbent. It has been optimised for acidic drugs such as 11-nor-delta-9-tetrahydrocannibinol-carboxylic acid, salicylic acid, ibuprofen, acetaminophen and other compounds that possess both non-polar and anionic characteristics.
Artikel-Nr:
(705-0045)
Lieferant:
Hach
Hersteller-Artikelnummer::
103769
Lokale Artikelnummer::
HACH103769
Beschreibung:
Test kit, Eisen (II), Messbereich: 0,02 - 3,00 mg/l
VE:
1 * 100 ST
Artikel-Nr:
(BLEG113407)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
113407
Lokale Artikelnummer::
BLEG113407
Beschreibung:
Anti-CD120b (TNF R Type II/p75) Armenian hamster Monoclonal Antibody [clone: TR75-89] (TotalSeq™-A0893)
VE:
1 * 10 µG
 This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
Cadmiumacetat Hydrat, Sigma-Aldrich®
Artikel-Nr:
(CBA059-1)
Lieferant:
Merck Millipore (Oncogene)
Hersteller-Artikelnummer::
CBA059-1
Lokale Artikelnummer::
ONCOCBA059-1
Beschreibung:
Das Calbiochem® Annexin V-FITC Apoptose-Detektions-Kit II ist ein nicht-isotopisches System, das zur Detektion von Phosphatidylserin auf der äußeren Schicht der Zellmembran apoptotischer Zellen mittels Durchflusszytometrie oder Fluoreszenzmikroskopie verwendet werden kann.
VE:
1 * 1 KIT
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
