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Methylpyrazolo[1,5-a]pyridin-3-carboxylat
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Methylpyrazolo[1,5-a]pyridin-3-carboxylat
Artikel-Nr:
(BOSSBS-6031R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6031R-A647
Lokale Artikelnummer::
BOSSBS-6031R-A647
Beschreibung:
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8541R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8541R-HRP
Lokale Artikelnummer::
BOSSBS-8541R-HRP
Beschreibung:
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2621R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2621R-A488
Lokale Artikelnummer::
BOSSBS-2621R-A488
Beschreibung:
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2621R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2621R-A750
Lokale Artikelnummer::
BOSSBS-2621R-A750
Beschreibung:
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4081R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4081R-HRP
Lokale Artikelnummer::
BOSSBS-4081R-HRP
Beschreibung:
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq].
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)hypoxantine (2’-FANA-I) ≥97%
Artikel-Nr:
(BOSSBS-11339R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11339R
Lokale Artikelnummer::
BOSSBS-11339R
Beschreibung:
Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11339R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11339R-A350
Lokale Artikelnummer::
BOSSBS-11339R-A350
Beschreibung:
Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7552R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7552R-HRP
Lokale Artikelnummer::
BOSSBS-7552R-HRP
Beschreibung:
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex. [provided by RefSeq, Nov 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12175R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12175R-A750
Lokale Artikelnummer::
BOSSBS-12175R-A750
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12175R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12175R-A680
Lokale Artikelnummer::
BOSSBS-12175R-A680
Beschreibung:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(APOSBIMN2031-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
BIMN2031-1G
Lokale Artikelnummer::
APOSBIMN2031-1G
Beschreibung:
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine (2’-FANA-T) ≥95%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-0400R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0400R-CY3
Lokale Artikelnummer::
BOSSBS-0400R-CY3
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(2-Hydroxy-3-N,N,N-trimethylamino)propyl-beta-cyclodextrin chloride
Artikel-Nr:
(BOSSBS-1657R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1657R-A488
Lokale Artikelnummer::
BOSSBS-1657R-A488
Beschreibung:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
VE:
1 * 100 µl
Lieferant:
Tonbo Biosciences
Beschreibung:
The A7R34 antibody is specific for mouse CD127, a 60 to 90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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