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diendo-3-Benzoyl-bicyclo[2.2.1]heptane-2-carboxylic+acid
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diendo-3-Benzoyl-bicyclo[2.2.1]heptane-2-carboxylic+acid
Artikel-Nr:
(BOSSBS-1697R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1697R
Lokale Artikelnummer::
BOSSBS-1697R
Beschreibung:
Anti-DEFA1 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13248R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13248R-A555
Lokale Artikelnummer::
BOSSBS-13248R-A555
Beschreibung:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2399R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2399R-A647
Lokale Artikelnummer::
BOSSBS-2399R-A647
Beschreibung:
Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5315R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5315R
Lokale Artikelnummer::
BOSSBS-5315R
Beschreibung:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6424R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6424R-CY5
Lokale Artikelnummer::
BOSSBS-6424R-CY5
Beschreibung:
SNX27 is involved in endocytic trafficking. In T lymphocytes it participates in the endocytic recycling pathway. SNX27 recruits PSCDBP and HT4R to early endosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6618R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6618R-A350
Lokale Artikelnummer::
BOSSBS-6618R-A350
Beschreibung:
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4726R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4726R-A647
Lokale Artikelnummer::
BOSSBS-4726R-A647
Beschreibung:
Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP 15. The cells within the body that produce GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP 15 to be a highly specific and sensitive marker for breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9551R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9551R-CY5
Lokale Artikelnummer::
BOSSBS-9551R-CY5
Beschreibung:
BEND2 is a 799 amino acid protein that contains two BEN domains. BEND2 exists as two alternatively spliced isoforms and is considered a complete proteome. BEN domain mediates protein–DNA and protein–protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND2 gene maps to human chromosome Xp22.13. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The X and Y chromosomes are the human sex chromosomes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9652R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9652R-HRP
Lokale Artikelnummer::
BOSSBS-9652R-HRP
Beschreibung:
C18orf1 is a 306 amino acid single-pass membrane protein that contains one LDL-receptor class A domain and belongs to the PMEPA1 family. C18orf1 exists as five alternatively spliced isoforms that display selective expression and are encoded by a gene that maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2905R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2905R-FITC
Lokale Artikelnummer::
BOSSBS-2905R-FITC
Beschreibung:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12176R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12176R-CY5
Lokale Artikelnummer::
BOSSBS-12176R-CY5
Beschreibung:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8332R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8332R-A647
Lokale Artikelnummer::
BOSSBS-8332R-A647
Beschreibung:
Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis which are thought important for seminal production and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0605R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0605R-CY5.5
Lokale Artikelnummer::
BOSSBS-0605R-CY5.5
Beschreibung:
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3102R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3102R-FITC
Lokale Artikelnummer::
BOSSBS-3102R-FITC
Beschreibung:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12157R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12157R-CY7
Lokale Artikelnummer::
BOSSBS-12157R-CY7
Beschreibung:
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2914R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2914R-CY5.5
Lokale Artikelnummer::
BOSSBS-2914R-CY5.5
Beschreibung:
Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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