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VARLP032522BAKR00001
Artikel-Nr:
(BOSSBS-0647R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0647R-A647
Lokale Artikelnummer::
BOSSBS-0647R-A647
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12900R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12900R-A555
Lokale Artikelnummer::
BOSSBS-12900R-A555
Beschreibung:
General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB212208-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB212208-100
Lokale Artikelnummer::
ABCAAB212208-100
Beschreibung:
Anti-IL-1R-2 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-11702R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11702R-FITC
Lokale Artikelnummer::
BOSSBS-11702R-FITC
Beschreibung:
The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-A555
Lokale Artikelnummer::
BOSSBS-12919R-A555
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12919R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12919R-CY3
Lokale Artikelnummer::
BOSSBS-12919R-CY3
Beschreibung:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5098R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5098R-A647
Lokale Artikelnummer::
BOSSBS-5098R-A647
Beschreibung:
Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM1086-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1086-50
Lokale Artikelnummer::
BTIUBNUM1086-50
Beschreibung:
This MAb reacts with a 45 kDa glycopeptide, which is a type II membrane glycoprotein with a transmembrane sequence near the NH2terminus. CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34 cells. The CD34 CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-7123R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7123R-A750
Lokale Artikelnummer::
BOSSBS-7123R-A750
Beschreibung:
Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).
VE:
1 * 100 µl
Lieferant:
BECTON DICKINSON MEDICAL
Beschreibung:
Plastic, coloured.
Artikel-Nr:
(BOSSBS-11693R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11693R-A680
Lokale Artikelnummer::
BOSSBS-11693R-A680
Beschreibung:
Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity. Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription. Contributes to the mRNA splicing efficiency and splice site selection. Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA and hence efficient RNA polymerase II (RNAp II) transcription termination. Required for the 3' transcriptional termination of PER1 and CRY2, thus playing an important role in the circadian rhythm regulation (By similarity). Involved in DNA double-strand breaks damage response generated by oxidative stress. In association with RRP45, targets the RNA exosome complex to sites of transcription-induced DNA damage. Plays a role in the development and maturation of germ cells: essential for male meiosis, acting at the interface of transcription and meiotic recombination, and in the process of gene silencing during meiotic sex chromosome inactivation (MSCI) (By similarity). May be involved in telomeric stability through the regulation of telomere repeat-containing RNA (TERRA) transcription. Plays a role in neurite outgrowth in hippocampal cells through FGF8-activated Signalling pathways. Inhibits retinoic acid-induced apoptosis.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of ~35 kDa, identified as CD74. It is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of ~35 kDa, identified as CD74. It is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of ~35 kDa, identified as CD74. It is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
Artikel-Nr:
(BOSSBS-4817R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4817R-FITC
Lokale Artikelnummer::
BOSSBS-4817R-FITC
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of ~35 kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma ( ).
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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