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Methyl+3-amino-7-fluorobenzo[b]thiophene-2-carboxylate
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Methyl+3-amino-7-fluorobenzo[b]thiophene-2-carboxylate
Artikel-Nr:
(BOSSBS-5885R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5885R-A555
Lokale Artikelnummer::
BOSSBS-5885R-A555
Beschreibung:
Myosin is a protein which is known to interact with actin in muscle and non-muscle cells. It contains two identical heavy chains and four light chains. Myosin molecules consist of two major regions: tails (rods) and heads. They aggregate into filaments through the tail region and interact with actin and with ATP through the head region. Multiple forms of myosin heavy chains exist for each muscle type-skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle. They are designated at type I (slow twitch) and type II (fast twitch).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0025M-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0025M-FITC
Lokale Artikelnummer::
BOSSBS-0025M-FITC
Beschreibung:
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1;PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Three alternative splice variants of PSEN1 have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(ROCK200-306-400)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
200-306-400
Lokale Artikelnummer::
ROCK200-306-400
Beschreibung:
This antibody was tested by ELISA and western blotting against both the native and recombinant forms of the Protein. This reagent may also be suitable other biotin-streptavidin based assays.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-6671R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6671R-CY5.5
Lokale Artikelnummer::
BOSSBS-6671R-CY5.5
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6671R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6671R-A488
Lokale Artikelnummer::
BOSSBS-6671R-A488
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9452R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9452R-HRP
Lokale Artikelnummer::
BOSSBS-9452R-HRP
Beschreibung:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9411R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9411R
Lokale Artikelnummer::
BOSSBS-9411R
Beschreibung:
TSPAN2 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. TSPAN2 may play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7741R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7741R-CY5.5
Lokale Artikelnummer::
BOSSBS-7741R-CY5.5
Beschreibung:
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6671R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6671R-A750
Lokale Artikelnummer::
BOSSBS-6671R-A750
Beschreibung:
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9082R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9082R
Lokale Artikelnummer::
BOSSBS-9082R
Beschreibung:
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8259R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8259R-CY7
Lokale Artikelnummer::
BOSSBS-8259R-CY7
Beschreibung:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5004R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5004R
Lokale Artikelnummer::
BOSSBS-5004R
Beschreibung:
PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8259R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8259R-CY3
Lokale Artikelnummer::
BOSSBS-8259R-CY3
Beschreibung:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
CF® dye picolyl azide reacts with alkyne to form 1,2,3-triazole by 1,3-dipolar Huisgen cycloaddition through the use of a much lower copper (I) concentration without sacrificing reaction efficiency. The selected CF® dyes are exceptionally bright and photostable, making them the perfect dye for fluorescence detection.
Artikel-Nr:
(BOSSBS-12142R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12142R-CY7
Lokale Artikelnummer::
BOSSBS-12142R-CY7
Beschreibung:
The membranes of myelinating Schwann cells are joined by tight, gap and adherens junctions, all of which are found in regions of noncompact myelin: the paranodal loops, incisures of Schmidt-Lanterman and mesaxons. Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and basolateral membranes. Pals-associated tight junction protein (PATJ), the human homolog of Drosophila Discs Lost, is differentially localized in myelinating Schwann cells. PATJ associates with Claudin-1, CRB1 (a transmembrane protein that plays a role in epithelial cell polarity and photoreceptor development), and Pals1 (a Lin-7 associated protein). The PATJ/Pals1/CRB1 complex can form a tripartite tight junction in epithelial cells crucial to their integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11709R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11709R-CY7
Lokale Artikelnummer::
BOSSBS-11709R-CY7
Beschreibung:
Mutations in the ALS2 gene result in a number of juvenile recessive motor neuron diseases (MNDs), including juvenile primary lateral sclerosis (JPLS), a recessive form of amyotrophic lateral sclerosis (ALS2); infantile onset ascending hereditary spastic paralysis (IAHSP); and a form of complicated hereditary spastic paraplegia (cHSP). The ALS2 gene encodes the Alsin protein. Alsin acts as a guanine nucleotide exchange factor for Rab5, a modulator of the endocytic pathway. Alsin is a cytosolic protein that is associated with small, punctate membrane structures. Therefore, Alsin may mediate membrane transport events, potentially linking endocytic processes and actin cytoskeleton remodeling. The ALS2 C-terminal-like protein (ALS2CL) also modulates Rab 5 activity.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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