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Artikel-Nr:
(BOSSBS-11159R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11159R-FITC
Lokale Artikelnummer::
BOSSBS-11159R-FITC
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH2 (protocadherin-2), also known as PCDHGC3 (protocadherin gamma subfamily C, 3) or PC43, is a 934 amino acid single-pass type I membrane protein that contains six cadherin domains and belongs to the protocadherin gamma family. Functioning as a calcium-dependent cell-adhesion protein, PCDH2 is thought to be involved in the establishment and maintenance of neuronal connections within the brain. Multiple isoforms of PCDH2 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13191R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13191R-FITC
Lokale Artikelnummer::
BOSSBS-13191R-FITC
Beschreibung:
FNDC3A is a 1,134 amino acid protein that belongs to the FNDC3 family of proteins. FNDC3A contains an N-terminal proline-rich region, nine fibronectin type-III domains (none of which contain an RGD sequence) and a hydrophobic C-terminal transmembranous helix. Expressed in a wide variety of tissues, FNDC3A localizes to Golgi vesicles and to the developing acrosome of spermatids. FNDC3A is believed to function in glycosaminoglycan and collagen synthesis. In mice, a mutation in the gene encoding FNDC3A causes male sterility due to defective adhesion between Sertoli cells and spermatids in the seminiferous epithelium. This suggests that FNDC3A plays an important role in spermatogenesis, possibly mediating or maintaining the adhesion between Sertoli cells and spermatids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9245R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9245R-CY5.5
Lokale Artikelnummer::
BOSSBS-9245R-CY5.5
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. MARCH10 (membrane-associated ring finger (C3HC4) 10), also known as RNF190 (ring finger protein 190) or MARCH-X, is an 808 amino acid protein with one RING-CH-type zinc finger domain. MARCH10 may function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13735R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13735R-A680
Lokale Artikelnummer::
BOSSBS-13735R-A680
Beschreibung:
SHROOM1 is an 852 amino acid protein that contains one ASD1 domain and one ASD2 domain. Localized to both the cytoplasm and the cytoskeleton, SHROOM1 interacts with Actin and is thought to be involved in microtubule assembly during cell elongation, possibly playing a role in the development of the nervous system. Multiple isoforms of SHROOM1 exist due to alternative splicing events. The gene encoding SHROOM1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1503R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1503R-CY5.5
Lokale Artikelnummer::
BOSSBS-1503R-CY5.5
Beschreibung:
This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterised by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [FUNCTION] Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15075R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15075R-CY5
Lokale Artikelnummer::
BOSSBS-15075R-CY5
Beschreibung:
Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11383R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11383R-A350
Lokale Artikelnummer::
BOSSBS-11383R-A350
Beschreibung:
ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12163R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12163R-A647
Lokale Artikelnummer::
BOSSBS-12163R-A647
Beschreibung:
CAPS2 is a 557 amino acid calcium-binding protein that is abundantly expressed, with highest expression found in placenta, testis, colon, lung and brain. CAPS2 contains three EF-hand domains and exists as three alternatively spliced isoforms. Suggested to play a role in large dense-core vesicle (LDCV) exocytosis, CAPS2 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11472R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11472R-HRP
Lokale Artikelnummer::
BOSSBS-11472R-HRP
Beschreibung:
RSHL3 is predicted to be a component of the radial spoke head based on homology with proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. RSHL3 (radial spoke head-like protein 3), also known as radial spoke head protein 4 homolog A, is a 716 amino acid protein that belongs to the flagellar radial spoke RSP4/6 family. Mutations in the RSHL3 gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Existing as three alternatively spliced isoforms, the RSHL3 gene contains 6 exons, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and P.falciparum, and maps to human chromosome 6q22.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9682R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9682R-A750
Lokale Artikelnummer::
BOSSBS-9682R-A750
Beschreibung:
C19orf46 is a 404 amino acid single-pass type IV membrane protein that belongs to the nesprin family. C19orf46 participates in the establishment of secretory epithelial morphology by inducing kinesin-dependent apical migration of the centrosome and Golgi apparatus as well as basal localisation of the nucleus. C19orf46 interacts with UKHC and KCL1, and exists as two alternatively spliced isoforms. C19orf46 contains a KASH domain, which consists of a transmembrane motif, mediates nuclear envelope targeting and binds to the SUN domain of SUN1 and SUN2. C19orf46 is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11064R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11064R-A647
Lokale Artikelnummer::
BOSSBS-11064R-A647
Beschreibung:
The Thrombospondin proteins, Thrombospondins 1-4 and Thrombospondin 5 (also designated COMP), compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell-surface proteins form complexes of both homo- and heteromultimers. Spondin-2, or Mindin, is also designated DIL-1 for its differential expression in cancerous and non-cancerous lung cells. Full-length SPON2 cDNA encodes a 331 amino acid protein with a domain arrangement similar to zebrafish F-Spondin and Mindin-1/Mindin-2: an FS1 domain, an FS2 domain, a hydrophobic signal sequence in the N-terminus and a Thrombospondin type I repeat. Immunoblot analysis demonstrates expression of dimers and oligomers in a concentration-dependent manner under nonreducing conditions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13602R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13602R-A350
Lokale Artikelnummer::
BOSSBS-13602R-A350
Beschreibung:
SLAIN1 is a 561 amino acid member of the SLAIN motif-containing family and is expressed in embryonic stem cells, as well as in lung, brain and testis, where it exists as two alternatively spliced isoforms. The gene encoding SLAIN1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9245R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9245R-CY5
Lokale Artikelnummer::
BOSSBS-9245R-CY5
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. MARCH10 (membrane-associated ring finger (C3HC4) 10), also known as RNF190 (ring finger protein 190) or MARCH-X, is an 808 amino acid protein with one RING-CH-type zinc finger domain. MARCH10 may function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11383R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11383R-HRP
Lokale Artikelnummer::
BOSSBS-11383R-HRP
Beschreibung:
ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12430R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12430R-A350
Lokale Artikelnummer::
BOSSBS-12430R-A350
Beschreibung:
DAAM2 is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13735R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13735R-A488
Lokale Artikelnummer::
BOSSBS-13735R-A488
Beschreibung:
SHROOM1 is an 852 amino acid protein that contains one ASD1 domain and one ASD2 domain. Localized to both the cytoplasm and the cytoskeleton, SHROOM1 interacts with Actin and is thought to be involved in microtubule assembly during cell elongation, possibly playing a role in the development of the nervous system. Multiple isoforms of SHROOM1 exist due to alternative splicing events. The gene encoding SHROOM1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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