tert-Butyl+2-amino-4-(trifluoromethyl)benzoate
Lieferant:
Sigma-Aldrich
Beschreibung:
Kaliumchlorid, Sigma-Aldrich®
Artikel-Nr:
(SIAL60126-1KG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
60126-1KG
Lokale Artikelnummer::
SIAL60126-1KG
Beschreibung:
Kaliumchlorid, Sigma-Aldrich®
VE:
1 * 1 kg
Artikel-Nr:
(HACH1476253)
Lieferant:
Hach
Hersteller-Artikelnummer::
1476253
Lokale Artikelnummer::
HACH1476253
Beschreibung:
Magnesiumchlorid 510 g/l in wässriger Lösung
VE:
1 * 1 L
Artikel-Nr:
(SERA26868.02)
Lieferant:
Serva
Hersteller-Artikelnummer::
26868.02
Lokale Artikelnummer::
SERA26868.02
Beschreibung:
Kaliumchlorid
VE:
1 * 1 kg
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Artikel-Nr:
(SIALR2252-10G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
R2252-10G
Lokale Artikelnummer::
SIALR2252-10G
Beschreibung:
Rubidiumchlorid, Sigma-Aldrich®
VE:
1 * 10 g
Artikel-Nr:
(BOSSBS-2927R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2927R-CY5.5
Lokale Artikelnummer::
BOSSBS-2927R-CY5.5
Beschreibung:
OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2927R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2927R-A750
Lokale Artikelnummer::
BOSSBS-2927R-A750
Beschreibung:
OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11040R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11040R-A750
Lokale Artikelnummer::
BOSSBS-11040R-A750
Beschreibung:
Best vitelliform macular dystrophy, known as Best disease, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision. Best disease is frequently a reflection of mutations in the Bestrophin gene, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells. Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium. Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current. Bestrophin Bestrophin 2,Bestrophin 3, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9036R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9036R-A750
Lokale Artikelnummer::
BOSSBS-9036R-A750
Beschreibung:
A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13706R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13706R-CY7
Lokale Artikelnummer::
BOSSBS-13706R-CY7
Beschreibung:
The calcium-activated chloride channel (CLCA) protein family, which includes the human homologs CLCA1 and CLCA2, display distinct tissue distribution patterns. CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins. CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins. CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis. CLCA2 expression is downregulated in breast cancer, therefore CLCA2 is thought to act as a tumor suppressor in normal cells. CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein. CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2672R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2672R-CY5
Lokale Artikelnummer::
BOSSBS-2672R-CY5
Beschreibung:
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(SIAL257125-200ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
257125-200ML
Lokale Artikelnummer::
SIAL257125-200ML
Beschreibung:
Phenylmagnesiumchlorid 2 mol/l in THF, Sigma-Aldrich®
VE:
1 * 200 mL
Lieferant:
Thermo Scientific
Beschreibung:
(Methoxymethyl)triphenylphosphoniumchlorid
Lieferant:
Spectrum Chemical
Beschreibung:
Choline Chloride, USP Dietary Supplement.
Lieferant:
Sigma-Aldrich
Beschreibung:
Bariumchlorid, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Magnesiumchlorid 1 mol/l (2 N) in wässriger Lösung, Sigma-Aldrich®
Preis auf Anfrage
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