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(±)11(12)-EET+methyl+ester
Artikel-Nr:
(BOSSBS-3418R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3418R-CY7
Lokale Artikelnummer::
BOSSBS-3418R-CY7
Beschreibung:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10380R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10380R-A488
Lokale Artikelnummer::
BOSSBS-10380R-A488
Beschreibung:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3418R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3418R-A350
Lokale Artikelnummer::
BOSSBS-3418R-A350
Beschreibung:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11067R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11067R-CY7
Lokale Artikelnummer::
BOSSBS-11067R-CY7
Beschreibung:
Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0183R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0183R-CY5
Lokale Artikelnummer::
BOSSBS-0183R-CY5
Beschreibung:
Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER alpha and ER beta. ER alpha and ER beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-Aand hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5214R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5214R-A680
Lokale Artikelnummer::
BOSSBS-5214R-A680
Beschreibung:
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant, and recessive forms of nephrogenic diabetes insipidus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2535R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2535R-A750
Lokale Artikelnummer::
BOSSBS-2535R-A750
Beschreibung:
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3862R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3862R-A680
Lokale Artikelnummer::
BOSSBS-3862R-A680
Beschreibung:
SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3862R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3862R-A750
Lokale Artikelnummer::
BOSSBS-3862R-A750
Beschreibung:
SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1927R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1927R-FITC
Lokale Artikelnummer::
BOSSBS-1927R-FITC
Beschreibung:
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
VE:
1 * 100 µl
Artikel-Nr:
(ROCK209-301-F12)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
209-301-F12
Lokale Artikelnummer::
ROCK209-301-F12
Beschreibung:
Anti-CD74 Antibody is suitable for WB, IP, Flow Cytometry, FACS, and IHC. Expect a band approximately ~33-35kDa Protein doublet corresponding to the molecular mass of the p33 and p35 forms of human CD74 on SDS PAGE immunoblots.
VE:
1 * 100 µG
Artikel-Nr:
(BSENC-1386-50)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
C-1386-50
Lokale Artikelnummer::
BSENC-1386-50
Beschreibung:
Neurofilaments contain three intermediate filament proteins: light (68 kDa), medium (160 kDa) and heavy (200 kDa). Neurofilament heavy (NF200 or NF-H) is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. This antibody binds primarily to the phosphorylated axonal forms of NF-H.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-1111R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1111R-A350
Lokale Artikelnummer::
BOSSBS-1111R-A350
Beschreibung:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9246R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9246R-A680
Lokale Artikelnummer::
BOSSBS-9246R-A680
Beschreibung:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5198R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5198R-FITC
Lokale Artikelnummer::
BOSSBS-5198R-FITC
Beschreibung:
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13229R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13229R-HRP
Lokale Artikelnummer::
BOSSBS-13229R-HRP
Beschreibung:
FUSIP1 is a member of the Serine/Arginine (SR) family of splicing factors. Members of the SR family all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. SR factors are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Expressed in a variety of tissues with low expression in kidney, liver and heart, FUSIP1 localizes to the cytoplasm and nuclear speckles. In its dephosphorylated form (occurring during M phase of the cell cycle), FUSIP1 functions as a potent general repressor of pre-mRNA splicing and can interact with U1 SnRNP 70. In its phosphorylated form, FUSIP1 interacts with Tra-2∫ and, together, they may cooperate in the regulation of splicing. Four isoforms exist for FUSIP1. In neurons, FUSIP1 isoforms may act to either positively or negatively regulate alternative splicing.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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