2-Methoxyethylisothiocyanat
Artikel-Nr:
(BOSSBS-5455R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5455R-CY7
Lokale Artikelnummer::
BOSSBS-5455R-CY7
Beschreibung:
Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6721R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6721R-A350
Lokale Artikelnummer::
BOSSBS-6721R-A350
Beschreibung:
KIRREL2 is an immunoglobulin super family gene, it has been found to be expressed in beta cells of pancreatic islets; KIRR2_HUMAN.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI31-107)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-107
Lokale Artikelnummer::
PRSI31-107
Beschreibung:
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded GABRP is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
VE:
1 * 50 µG
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Nicotinamid 99%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,6-Anhydro-β-D-glucofuranose ≥98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,6-Anhydro-β-D-cellotriose ≥98%
Lieferant:
Thermo Scientific
Beschreibung:
3-Amino-3-phenyl-1-propanol 94%
Artikel-Nr:
(BOSSBS-5347R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5347R-CY5.5
Lokale Artikelnummer::
BOSSBS-5347R-CY5.5
Beschreibung:
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq].eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5347R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5347R-A555
Lokale Artikelnummer::
BOSSBS-5347R-A555
Beschreibung:
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq].eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Tolmetin acyl-β-D-glucuronide ≥95%
Artikel-Nr:
(BOSSBS-5455R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5455R-CY3
Lokale Artikelnummer::
BOSSBS-5455R-CY3
Beschreibung:
Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3425R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3425R-CY3
Lokale Artikelnummer::
BOSSBS-3425R-CY3
Beschreibung:
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6646R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6646R-A750
Lokale Artikelnummer::
BOSSBS-6646R-A750
Beschreibung:
Modulator of beta-cells function, acting through the up-regulation of PDX1 and NKX6-1 and consequent stimulation of insulin secretion in response to glucose.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2073R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2073R-CY5.5
Lokale Artikelnummer::
BOSSBS-2073R-CY5.5
Beschreibung:
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2073R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2073R-CY7
Lokale Artikelnummer::
BOSSBS-2073R-CY7
Beschreibung:
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2073R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2073R-A555
Lokale Artikelnummer::
BOSSBS-2073R-A555
Beschreibung:
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.
VE:
1 * 100 µl
Preis auf Anfrage
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