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2-(4-Fluorobenzenesulphamido)propanoic+acid
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2-(4-Fluorobenzenesulphamido)propanoic+acid
Artikel-Nr:
(BOSSBS-7651R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7651R-A555
Lokale Artikelnummer::
BOSSBS-7651R-A555
Beschreibung:
Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognized as specific for DNA; it was the first DNase to be crystallized; and it was the first DNase for which a specific protein inhibitor was characterized. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesized in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13644R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13644R-A647
Lokale Artikelnummer::
BOSSBS-13644R-A647
Beschreibung:
The transcription factor NFkB is retained in the cytoplasm in an inactive form by the inhibitory protein IkB. Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in the targeted degradation of IkB (1). IkB kinase alpha (IKK alpha), previously designated CHUK (2), interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation, serines 32 and 36 (3). IKKalpha appears to be critical for NFkB activation in response to proinflammatory cytokines (4). Phosphorylation of the IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1 (5). The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma (also designated NEMO), and each appears to make essential contributions to IkB phosphorylation (6). IKAP (IKK-complex-associated protein) is a protein that acts as a scaffold, interacting with NIK, IKK alpha and IKK beta and assembling them into an active kinase complex (7,8)
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7651R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7651R-A680
Lokale Artikelnummer::
BOSSBS-7651R-A680
Beschreibung:
Deoxyribonuclease I gene is approximately 3.2 kb long with 9 exons separated by 8 introns. In the form of a bovine pancreatic enzyme preparation, it occupies an important place in the history of protein chemistry and enzymology: it was the first enzyme to be recognised as specific for DNA; it was the first DNase to be crystallised; and it was the first DNase for which a specific protein inhibitor was characterised. DNase I is a Ca2+ and Mg2+ dependant endonuclease. DNase I is synthesised in the pancreas and stored in zymogen granules. It has been used to reduce the viscosity of cystic fibrosis sputum. A DNase I-like enzyme appears to catalyze the degradation of chromatin to oligo- and mononucleosomes during apoptosis. A recent study has demonstrated an endonuclease with activity and antigenicity indistinguishable from DNase I in thymocytes, cells susceptible to apoptosis. DNase I is an endonuclease that hydrolyzes double-stranded or single stranded DNA preferentially at sites adjacent to pyrimidine nucleotides. The product of hydrolysis is a complex mixture of 5'-phosphate mononucleotides and oligonucleotides. In the presence of Mg ion, DNase I attacks each strand of DNA independently and the cleavage sites are random.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13644R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13644R-CY7
Lokale Artikelnummer::
BOSSBS-13644R-CY7
Beschreibung:
The transcription factor NFkB is retained in the cytoplasm in an inactive form by the inhibitory protein IkB. Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in the targeted degradation of IkB (1). IkB kinase alpha (IKK alpha), previously designated CHUK (2), interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation, serines 32 and 36 (3). IKKalpha appears to be critical for NFkB activation in response to proinflammatory cytokines (4). Phosphorylation of the IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1 (5). The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma (also designated NEMO), and each appears to make essential contributions to IkB phosphorylation (6). IKAP (IKK-complex-associated protein) is a protein that acts as a scaffold, interacting with NIK, IKK alpha and IKK beta and assembling them into an active kinase complex (7,8)
VE:
1 * 100 µl
Artikel-Nr:
(APOSPC446063-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC446063-1G
Lokale Artikelnummer::
APOSPC446063-1G
Beschreibung:
4-(6-Dimethylamino-4-trifluoromethylpyridin-2-yl)benzoic acid methyl ester
VE:
1 * 1 g
Artikel-Nr:
(HEWL5065-9948)
Lieferant:
Agilent
Hersteller-Artikelnummer::
5065-9948
Lokale Artikelnummer::
HEWL5065-9948
Beschreibung:
Fitting screws, stainless steel, 10-32, 4 mm
VE:
1 * 5 ST
Artikel-Nr:
(APOSPC8417-500MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC8417-500MG
Lokale Artikelnummer::
APOSPC8417-500MG
Beschreibung:
4-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}-2-buten-1-ol 97%
VE:
1 * 500 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
tert-Butyl-2-[3-chloro-5-(trifluoromethyl)-2-pyridyl]-2-cyanoacetate
Artikel-Nr:
(APOSOR17551-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR17551-1G
Lokale Artikelnummer::
APOSOR17551-1G
Beschreibung:
(5,6-Dichlor-3-pyridinyl)methanol 95+%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Methyl-4-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino}butanoate
Artikel-Nr:
(ICNA0202826)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
0202826
Lokale Artikelnummer::
ICNA0202826
Beschreibung:
Siliciumdioxid, Ecochrom™ 32-63 µm
VE:
1 * 25 kg
Artikel-Nr:
(APOSOR345604-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR345604-25G
Lokale Artikelnummer::
APOSOR345604-25G
Beschreibung:
1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid 97%
VE:
1 * 25 g
Lieferant:
MEMMERT
Beschreibung:
Einsatzgestell für Schüttelvorrichtung für 45 Reagenzgläser Ø 32 mm, Für: WTB24
Lieferant:
Agilent
Beschreibung:
PEEK adapter 1/4-28 to 10-32, PEEK
Lieferant:
Alfa Aesar
Beschreibung:
Fmoc-L-4-pyridylalanine 95%
Artikel-Nr:
(05211-2.5L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
05211-2.5L
Lokale Artikelnummer::
HONC05211-2.5L
Beschreibung:
Natriumhydroxid ≥32% in wässriger Lösung, Purum, Fluka™
VE:
1 * 2,5 L
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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