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3-(Trifluormethylthio)benzonitril
Artikel-Nr:
(BOSSBS-9577R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9577R-A488
Lokale Artikelnummer::
BOSSBS-9577R-A488
Beschreibung:
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6383R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6383R-A647
Lokale Artikelnummer::
BOSSBS-6383R-A647
Beschreibung:
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0641R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0641R-A680
Lokale Artikelnummer::
BOSSBS-0641R-A680
Beschreibung:
Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognise one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognises the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognises the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10239R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10239R-A555
Lokale Artikelnummer::
BOSSBS-10239R-A555
Beschreibung:
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6421R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6421R-A555
Lokale Artikelnummer::
BOSSBS-6421R-A555
Beschreibung:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9119R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9119R-A488
Lokale Artikelnummer::
BOSSBS-9119R-A488
Beschreibung:
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0641R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0641R-A647
Lokale Artikelnummer::
BOSSBS-0641R-A647
Beschreibung:
Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9577R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9577R-FITC
Lokale Artikelnummer::
BOSSBS-9577R-FITC
Beschreibung:
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12278R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12278R-A488
Lokale Artikelnummer::
BOSSBS-12278R-A488
Beschreibung:
SOHLH1 is a 328 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one bHLH domain through which it may function as a transcription factor during oogenesis and spermatogenesis. The gene encoding SOHLH1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9119R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9119R-A350
Lokale Artikelnummer::
BOSSBS-9119R-A350
Beschreibung:
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Lieferant:
VWR Collection
Beschreibung:
Die Mikrozentrifugen Micro Star 21 und 21R vereinen Leistung, Vielseitigkeit und Komfort in einem sicheren, kompakten und benutzerfreundlichen Laborgerät. Sowohl die belüftete Micro Star 21 als auch die gekühlte Micro Star 21R sind eine ausgezeichnete Wahl für routinemäßige Probenvorbereitungsprozesse und für High-End-Forschungsanwendungen. Der spezielle Biocontainment-Rotordeckel zum Öffnen und Schließen des Rotors mit einem Klick verkürzt die Probenwechsel im Vergleich zu Schraubdeckeln.
Artikel-Nr:
(BOSSBS-11710R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11710R-FITC
Lokale Artikelnummer::
BOSSBS-11710R-FITC
Beschreibung:
The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12402R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12402R-FITC
Lokale Artikelnummer::
BOSSBS-12402R-FITC
Beschreibung:
RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8034R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8034R-A647
Lokale Artikelnummer::
BOSSBS-8034R-A647
Beschreibung:
Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0651R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0651R-A555
Lokale Artikelnummer::
BOSSBS-0651R-A555
Beschreibung:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0651R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0651R-A680
Lokale Artikelnummer::
BOSSBS-0651R-A680
Beschreibung:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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