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2-(Carboxymethyl)-6-fluorobenzoic+acid
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2-(Carboxymethyl)-6-fluorobenzoic+acid
Lieferant:
VWR Chemicals
Beschreibung:
EGTA (Ethylenglycolbis(2-aminoethylether)-N,N,N',N'-tetraessigsäure) ≥97%, weißes kristallines Pulver, Ultrareine Qualität
Artikel-Nr:
(BLDPBD01405549-100)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD01405549-100
Lokale Artikelnummer::
BLDPBD01405549-100
Beschreibung:
7,9-Bis(2,6-diethylphenyl)-7H-acenaphtho[1,2-d]imidazol-9-ium chloride 97%
VE:
1 * 100 mg
Artikel-Nr:
(34306-50MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
34306-50MG
Lokale Artikelnummer::
SUPL34306-50MG
Beschreibung:
Organic Standard, Quizalofop-ethyl
VE:
1 * 50 mg
Artikel-Nr:
(92107.010)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC92107.010
Beschreibung:
Organic Standard, Tetrabromobisphenol A bis(2, 3-dibromopropyl ether), 100 µg/ml in toluene, Packung: Glass ampoule/vial
VE:
1 * 1 mL
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5,7-Bis(trifluoromethyl)-3-cyano-2-(cyanomethyl)pyrazolo[1,5-A]pyrimidine 97%
Artikel-Nr:
(USBI0014-24E)
Lieferant:
US Biological
Hersteller-Artikelnummer::
0014-24E
Lokale Artikelnummer::
USBI0014-24E
Beschreibung:
Anti-14-3-3 delta/zeta Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BLDPBD00987839-250)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD00987839-250
Lokale Artikelnummer::
BLDPBD00987839-250
Beschreibung:
(S,S,S)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine ≥97%, ee 99%
VE:
1 * 250 mg
Artikel-Nr:
(BWRLBS6305)
Lieferant:
Bioworld Technology
Hersteller-Artikelnummer::
BS6305
Lokale Artikelnummer::
BWRLBS6305
Beschreibung:
Recombinant full length Human 14-3-3 sigma.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-7736R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7736R-A350
Lokale Artikelnummer::
BOSSBS-7736R-A350
Beschreibung:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7736R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7736R-FITC
Lokale Artikelnummer::
BOSSBS-7736R-FITC
Beschreibung:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9201R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9201R-A350
Lokale Artikelnummer::
BOSSBS-9201R-A350
Beschreibung:
IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.
VE:
1 * 100 µl
Artikel-Nr:
(STMC100-1381)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1381
Lokale Artikelnummer::
STMC100-1381
Beschreibung:
Stimulating T cells with SARS-CoV-2 (Spike Protein) Delta/B.1.617.2 WT reference peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. This peptide pool is a lyophilised mixture of 27 peptides from the spike glycoprotein of the wild-type SARS-CoV-2 virus. Consisting of the wild-type peptides that correspond to the mutated portions of the spike protein found in the SARS-CoV-2 Delta variant (B.1.617.2), this pool is recommended to be used as a reference for the SARS-CoV-2 (Spike Protein) Delta/B.1.617.2 Mutation Peptide Pool. Through interactions with the angiotensin-converting enzyme 2 (ACE2) receptor, the spike protein enables the virus to attach to the cell membrane, and plays a critical role in viral entry (Hoffmann <i>et al.</i>; Walls <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
 This is a MarketSource item. Additional charges may apply
Lieferant:
Alfa Aesar
Beschreibung:
1,1'-Binaphthalin-2,2'-diylbis(diphenylphosphin) ≥98%
Artikel-Nr:
(BOSSBS-1650R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1650R-CY5
Lokale Artikelnummer::
BOSSBS-1650R-CY5
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1650R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1650R-CY3
Lokale Artikelnummer::
BOSSBS-1650R-CY3
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(ABCAAB111856-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB111856-100
Lokale Artikelnummer::
ABCAAB111856-100
Beschreibung:
Anti-14-3-3 beta/zeta Rabbit Polyclonal Antibody
VE:
1 * 100 µG
This is a MarketSource item. Additional charges may apply
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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