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1-Phenyl-2-(quinoxalin-2-yl)ethanol
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1-Phenyl-2-(quinoxalin-2-yl)ethanol
Artikel-Nr:
(PRSI29-382)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-382
Lokale Artikelnummer::
PRSI29-382
Beschreibung:
SARS belongs to the class II amino-acyl tRNA family. The enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts.This gene belongs to the class II amino-acyl tRNA family. The encoded enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts.
VE:
1 * 100 µG
Artikel-Nr:
(HIMEM1003-500G)
Lieferant:
HIMEDIA
Hersteller-Artikelnummer::
M1003-500G
Lokale Artikelnummer::
HIMEM1003-500G
Beschreibung:
Controlled quality of materials. The different media comply with international standards. For the method of preparation and technical data sheets, please contact the customer service.
VE:
1 * 500 g
Artikel-Nr:
(PRSI31-249)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-249
Lokale Artikelnummer::
PRSI31-249
Beschreibung:
GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
VE:
1 * 100 µG
Artikel-Nr:
(ABCRAB128849.0500)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB128849.0500
Lokale Artikelnummer::
ABCRAB128849.0500
Beschreibung:
Metallocenes, Derivatives & Cp Precursors, Volatile Organometallics for CVD & ALD, Volatile Precursors for CVD
VE:
1 * 500 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(AATB80001)
Lieferant:
AAT BIOQUEST
Hersteller-Artikelnummer::
80001
Lokale Artikelnummer::
AATB80001
Beschreibung:
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of 2 µM.
VE:
1 * 1 mg
Artikel-Nr:
(PRSI76-344)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-344
Lokale Artikelnummer::
PRSI76-344
Beschreibung:
The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
VE:
1 * 0,1 mg
New Product
Lieferant:
Honeywell Chemicals
Beschreibung:
EDTA (Ethylendiamintetraessigsäure) ≥99,0% für die Komplexometrie, Fluka™
Artikel-Nr:
(PRSI26-759)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-759
Lokale Artikelnummer::
PRSI26-759
Beschreibung:
DCAL1 is a type II transmembrane, C-type lectin-like protein expressed on dendritic cells (DCs) and B cells. It interacts with subsets of T cells as a costimulatory molecule that enhances interleukin-4 (IL4; MIM 147780) production.DCAL1 is a type II transmembrane, C-type lectin-like protein expressed on dendritic cells (DCs) and B cells. It interacts with subsets of T cells as a costimulatory molecule that enhances interleukin-4 (IL4; MIM 147780) production.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-760)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-760
Lokale Artikelnummer::
PRSI26-760
Beschreibung:
DCAL1 is a type II transmembrane, C-type lectin-like protein expressed on dendritic cells (DCs) and B cells. It interacts with subsets of T cells as a costimulatory molecule that enhances interleukin-4 (IL4; MIM 147780) production. DCAL1 is a type II transmembrane, C-type lectin-like protein expressed on dendritic cells (DCs) and B cells. It interacts with subsets of T cells as a costimulatory molecule that enhances interleukin-4 (IL4; MIM 147780) production.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1687R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1687R-A750
Lokale Artikelnummer::
BOSSBS-1687R-A750
Beschreibung:
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterised by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localisation, and cellular function. Phosphorylates TPM1, enhancing stress fibre formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. Phosphorylates PRKD1 and regulates JNK signaling by binding and activating PRKD1 under oxidative stress. Phosphorylates BECN1, reducing its interaction with BCL2 and BCL2L1 and promoting the induction of autophagy. Phosphorylates TSC2, disrupting the TSC1-TSC2 complex and stimulating mTORC1 activity in a growth factor-dependent pathway. Phosphorylates RPS6, MYL9 and DAPK3. Acts as a signaling amplifier of NMDA receptors at extrasynaptic sites for mediating brain damage in stroke. Cerebral ischemia recruits DAPK1 into the NMDA receptor complex and it phosphorylates GRINB at Ser-133 inducing injurious Ca(2+) influx through NMDA receptor channels, resulting in an irreversible neuronal death. Required together with DAPK3 for phosphorylation of RPL13A upon interferon-gamma activation which is causing RPL13A involvement in transcript-selective translation inhibition. Isoform 2 cannot induce apoptosis but can induce membrane blebbing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4005R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4005R-A488
Lokale Artikelnummer::
BOSSBS-4005R-A488
Beschreibung:
Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. The ATG12-ATG5 conjugate also negatively regulates the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT2 via the autophagic pathway. May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6252R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6252R
Lokale Artikelnummer::
BOSSBS-6252R
Beschreibung:
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
VE:
1 * 100 µl
Lieferant:
Spectrum Chemical
Beschreibung:
Melamine statement (available upon request)
BSE/TSE statement (available upon request) Allergen statement (available upon request)
Artikel-Nr:
(786-140RF-II)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
786-140RF-II
Lokale Artikelnummer::
GENO786-140RF-II
Beschreibung:
GELPLATE-clean™ removes proteins, nucleic acids, fats, lipids, radioisotopes and other contaminants from electrophoresis gel plates. It is suitable for sequencing and protein electrophoresis gel plates.
VE:
1 * 1 L
Artikel-Nr:
(PRSI96-663)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-663
Lokale Artikelnummer::
PRSI96-663
Beschreibung:
S100 calcium-binding protein A10 (S100A10), a member of the S100 family of proteins containing two EF-hand calcium-binding motifs, is also known as protein S100-A10, calpactin I light chain, cellular ligand of annexin II, p10 protein and p11, which can be found as a free monomer, a homodimer, or a heterotetramer composed of a p11 dimer complex with two molecules of annexin II. S100A10 is an integral part of cellular structural scaffolding that interacts with plasma membrane proteins through its association with annexin II. S100A10 also works together with cytosolic and peripheral membrane-associated proteins such as AHNAK in the development of the intracellular membrane. Furthermore,S100A10 has been implicated in the transportation of proteins involved in mood regulation, nociception, and cell polarization. Complexed with the annexin II, S100A10 binds receptor and channel proteins and guides them to the cell surface, resulting in increased membrane localization and consequent magnified functional expression of these proteins.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-1687R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1687R-HRP
Lokale Artikelnummer::
BOSSBS-1687R-HRP
Beschreibung:
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. Phosphorylates PRKD1 and regulates JNK signaling by binding and activating PRKD1 under oxidative stress. Phosphorylates BECN1, reducing its interaction with BCL2 and BCL2L1 and promoting the induction of autophagy. Phosphorylates TSC2, disrupting the TSC1-TSC2 complex and stimulating mTORC1 activity in a growth factor-dependent pathway. Phosphorylates RPS6, MYL9 and DAPK3. Acts as a signaling amplifier of NMDA receptors at extrasynaptic sites for mediating brain damage in stroke. Cerebral ischemia recruits DAPK1 into the NMDA receptor complex and it phosphorylates GRINB at Ser-133 inducing injurious Ca(2+) influx through NMDA receptor channels, resulting in an irreversible neuronal death. Required together with DAPK3 for phosphorylation of RPL13A upon interferon-gamma activation which is causing RPL13A involvement in transcript-selective translation inhibition. Isoform 2 cannot induce apoptosis but can induce membrane blebbing.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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