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Benzoic+acid-acyl-\\\\u03B2-D-glucuronide
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Benzoic+acid-acyl-\\\\u03B2-D-glucuronide
Artikel-Nr:
(BOSSBS-1388R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1388R-A647
Lokale Artikelnummer::
BOSSBS-1388R-A647
Beschreibung:
Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g. TNF-inducible RELA/p65 activation and IL-6-inducible STAT3 signaling). Promotes RNA synthesis in genetic programs for cell growth, differentiation and viral pathogenesis. P-TEFb is also involved in cotranscriptional histone modification, mRNA processing and mRNA export. Modulates a complex network of chromatin modifications including histone H2B monoubiquitination (H2Bub1), H3 lysine 4 trimethylation (H3K4me3) and H3K36me3; integrates phosphorylation during transcription with chromatin modifications to control co-transcriptional histone mRNA processing. The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro. Replication stress response protein; the CDK9/cyclin-K complex is required for genome integrity maintenance, by promoting cell cycle recovery from replication arrest and limiting single-stranded DNA amount in response to replication stress, thus reducing the breakdown of stalled replication forks and avoiding DNA damage. In addition, probable function in DNA repair of isoform 2 via interaction with KU70/XRCC6. Promotes cardiac myocyte enlargement. RPB1/POLR2A phosphorylation on 'Ser-2' in CTD activates transcription. AR phosphorylation modulates AR transcription factor promoter selectivity and cell growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1388R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1388R-HRP
Lokale Artikelnummer::
BOSSBS-1388R-HRP
Beschreibung:
Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g. TNF-inducible RELA/p65 activation and IL-6-inducible STAT3 signaling). Promotes RNA synthesis in genetic programs for cell growth, differentiation and viral pathogenesis. P-TEFb is also involved in cotranscriptional histone modification, mRNA processing and mRNA export. Modulates a complex network of chromatin modifications including histone H2B monoubiquitination (H2Bub1), H3 lysine 4 trimethylation (H3K4me3) and H3K36me3; integrates phosphorylation during transcription with chromatin modifications to control co-transcriptional histone mRNA processing. The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro. Replication stress response protein; the CDK9/cyclin-K complex is required for genome integrity maintenance, by promoting cell cycle recovery from replication arrest and limiting single-stranded DNA amount in response to replication stress, thus reducing the breakdown of stalled replication forks and avoiding DNA damage. In addition, probable function in DNA repair of isoform 2 via interaction with KU70/XRCC6. Promotes cardiac myocyte enlargement. RPB1/POLR2A phosphorylation on 'Ser-2' in CTD activates transcription. AR phosphorylation modulates AR transcription factor promoter selectivity and cell growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1388R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1388R-A680
Lokale Artikelnummer::
BOSSBS-1388R-A680
Beschreibung:
Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors (e.g. TNF-inducible RELA/p65 activation and IL-6-inducible STAT3 signaling). Promotes RNA synthesis in genetic programs for cell growth, differentiation and viral pathogenesis. P-TEFb is also involved in cotranscriptional histone modification, mRNA processing and mRNA export. Modulates a complex network of chromatin modifications including histone H2B monoubiquitination (H2Bub1), H3 lysine 4 trimethylation (H3K4me3) and H3K36me3; integrates phosphorylation during transcription with chromatin modifications to control co-transcriptional histone mRNA processing. The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro. Replication stress response protein; the CDK9/cyclin-K complex is required for genome integrity maintenance, by promoting cell cycle recovery from replication arrest and limiting single-stranded DNA amount in response to replication stress, thus reducing the breakdown of stalled replication forks and avoiding DNA damage. In addition, probable function in DNA repair of isoform 2 via interaction with KU70/XRCC6. Promotes cardiac myocyte enlargement. RPB1/POLR2A phosphorylation on 'Ser-2' in CTD activates transcription. AR phosphorylation modulates AR transcription factor promoter selectivity and cell growth.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Chrom(II)chlorid, Sigma-Aldrich®
Artikel-Nr:
(YSIL2363)
Lieferant:
YSI LIFE SCIENCE
Hersteller-Artikelnummer::
2363
Lokale Artikelnummer::
YSIL2363
Beschreibung:
Kaliumhexacyanoferrat(II)
VE:
1 * 125 mL
Artikel-Nr:
(BOSSBS-3756R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3756R-FITC
Lokale Artikelnummer::
BOSSBS-3756R-FITC
Beschreibung:
PPP1A is a serine/threonine protein phosphatase catalytic subunit that is essential for regulating cellular stress responses in eukaryotes. It binds to magnesium or manganese ions and exists as a monomer. It is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1A is involved in the regulation long term synaptic plasticity and may play an important role in dephosphorylating substrates such as Ca2+/calmodulin dependent protein kinase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3756R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3756R-CY3
Lokale Artikelnummer::
BOSSBS-3756R-CY3
Beschreibung:
PPP1A is a serine/threonine protein phosphatase catalytic subunit that is essential for regulating cellular stress responses in eukaryotes. It binds to magnesium or manganese ions and exists as a monomer. It is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1A is involved in the regulation long term synaptic plasticity and may play an important role in dephosphorylating substrates such as Ca2+/calmodulin dependent protein kinase II.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0015R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0015R-HRP
Lokale Artikelnummer::
BOSSBS-0015R-HRP
Beschreibung:
The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7718R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7718R-A555
Lokale Artikelnummer::
BOSSBS-7718R-A555
Beschreibung:
CAPD2 is a regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. It may target the condensin complex to DNA via its C-terminal domain (referenced from Swissprot).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3385R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3385R-A350
Lokale Artikelnummer::
BOSSBS-3385R-A350
Beschreibung:
The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily. It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells.
VE:
1 * 100 µl
Artikel-Nr:
(NOVUNBP2-89746-50)
Lieferant:
Novus Biologicals
Hersteller-Artikelnummer::
NBP2-89746-50
Lokale Artikelnummer::
NOVUNBP2-89746-50
Beschreibung:
The protein encoded by the IL22 RA2 gene is a soluble class II cytokine receptor. This protein has been shown to specificallybind to interleukin 22 (IL22), block the interaction of IL22 with its cell surface receptor, and thus inhibit IL22activity. This protein functions as an IL22 antagonist, and may be important in the regulation of inflammatoryresponse. Three alternatively spliced transcript variants encoding distinct isoforms have been described. (provided byRefSeq)
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-13254R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13254R-CY3
Lokale Artikelnummer::
BOSSBS-13254R-CY3
Beschreibung:
This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6338R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6338R-FITC
Lokale Artikelnummer::
BOSSBS-6338R-FITC
Beschreibung:
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4730R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4730R-A350
Lokale Artikelnummer::
BOSSBS-4730R-A350
Beschreibung:
Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6338R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6338R-A488
Lokale Artikelnummer::
BOSSBS-6338R-A488
Beschreibung:
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4038R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4038R
Lokale Artikelnummer::
BOSSBS-4038R
Beschreibung:
SLC25A13 is a member of the mitochondrial carrier family. It contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. It catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in the SLC25A13 gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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