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Sulindac+sulphone-acyl-\u03B2-D-glucuronide
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Sulindac+sulphone-acyl-\u03B2-D-glucuronide
Artikel-Nr:
(PRSI31-223)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-223
Lokale Artikelnummer::
PRSI31-223
Beschreibung:
CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI2325)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2325
Lokale Artikelnummer::
PRSI2325
Beschreibung:
Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI2327)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2327
Lokale Artikelnummer::
PRSI2327
Beschreibung:
Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI3195)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3195
Lokale Artikelnummer::
PRSI3195
Beschreibung:
Caspase-12 Antibody: (Large)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI77-179)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-179
Lokale Artikelnummer::
PRSI77-179
Beschreibung:
The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc epsilon Receptor I alpha subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PRSI77-174)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-174
Lokale Artikelnummer::
PRSI77-174
Beschreibung:
The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro/in vivo.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PHR1728-40MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
PHR1728-40MG
Lokale Artikelnummer::
SUPLPHR1728-40MG
Beschreibung:
Organic Standard, GLIMEPIRIDE 3-ISOMER
VE:
1 * 40 mg
Lieferant:
Alfa Aesar
Beschreibung:
2-Cyan-3-methylpyridin ≥98%
Artikel-Nr:
(PRSI77-177)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-177
Lokale Artikelnummer::
PRSI77-177
Beschreibung:
The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc epsilon Receptor I alpha subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
VE:
1 * 0,025 mg
New Product
Lieferant:
BLD PHARMATECH GMBH
Beschreibung:
2-Cyan-3-methylpyridin 98%
Artikel-Nr:
(PRSI90-469)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-469
Lokale Artikelnummer::
PRSI90-469
Beschreibung:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-466)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-466
Lokale Artikelnummer::
PRSI90-466
Beschreibung:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI90-465)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-465
Lokale Artikelnummer::
PRSI90-465
Beschreibung:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-454)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-454
Lokale Artikelnummer::
PRSI96-454
Beschreibung:
Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI76-499)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-499
Lokale Artikelnummer::
PRSI76-499
Beschreibung:
The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor alpha (IL-2R alpha, also known as CD25). CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor beta chain (CD122) and the common gamma chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI77-176)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-176
Lokale Artikelnummer::
PRSI77-176
Beschreibung:
The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc epsilon Receptor I alpha subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
VE:
1 * 0,1 mg
New Product
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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