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5-Oxaspiro[3.5]nonan-8-one
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5-Oxaspiro[3.5]nonan-8-one
Artikel-Nr:
(BOSSBS-13339R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13339R-A680
Lokale Artikelnummer::
BOSSBS-13339R-A680
Beschreibung:
GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4820R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4820R-A750
Lokale Artikelnummer::
BOSSBS-4820R-A750
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0522R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0522R-FITC
Lokale Artikelnummer::
BOSSBS-0522R-FITC
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0522R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0522R-A488
Lokale Artikelnummer::
BOSSBS-0522R-A488
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 30652-11-0
Artikel-Nr:
(BOSSBS-11705R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11705R-A680
Lokale Artikelnummer::
BOSSBS-11705R-A680
Beschreibung:
AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within the cell. AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, suggesting a role in tumour suppression. Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukaemia (AML), implicating a role for AIP1 fusion proteins in tumourigenesis.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
6-Chlor-4-chinazolon 98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4'-Ethylacetophenon 98%
Artikel-Nr:
(BOSSBS-4819R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4819R-CY7
Lokale Artikelnummer::
BOSSBS-4819R-CY7
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Hydroxy-4'-methoxyacetophenon 97%
Artikel-Nr:
(BOSSBS-11733R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-A555
Lokale Artikelnummer::
BOSSBS-11733R-A555
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11733R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-A350
Lokale Artikelnummer::
BOSSBS-11733R-A350
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11733R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-A647
Lokale Artikelnummer::
BOSSBS-11733R-A647
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
Lieferant:
DISCOVER ECHO
Beschreibung:
Dieses automatisierte ‚All-in-One‘-Hybridmikroskop kann für aufrechte und invertierte Beobachtungsmethoden verwendet werden.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Inactive analog of genistein, useful as a negativecontrol for genistein and other tyrosine inhibitors
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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