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Artikel-Nr:
(USBII0610-21)
Lieferant:
US Biological
Hersteller-Artikelnummer::
I0610-21
Lokale Artikelnummer::
USBII0610-21
Beschreibung:
Anti-Ice Protease Activating Factor Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3936R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3936R-CY7
Lokale Artikelnummer::
BOSSBS-3936R-CY7
Beschreibung:
Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3419R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3419R-CY5
Lokale Artikelnummer::
BOSSBS-3419R-CY5
Beschreibung:
Smad2 is a 58 kDa member of a family of proteins involved in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor-regulated Smad's, activin/TGF alpha receptor-regulated (Smad2 and 3) or BMP receptor regulated (Smad1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smad's; and the inhibitory Smad's, (Smad6 and Smad7). Smad2 consists of two highly conserved domains, the N terminal Mad homology (MH1) and the C-terminal Mad homology 2 (MH2) domains. The MH1 domain binds DNA and regulates nuclear import and transcription while the MH2 domain conserved among all the Smad's regulates Smad2 oligomerization and binding to cytoplasmic adaptors and transcription factors. Activated Smad2 associates with Smad4 and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. This translocation of Smad2 (as well as Smad3) into the nucleus is a central event in TGF beta signaling. Phosphorylation of threonine 8 in the calmodulin binding region of the MH1 domain by extracellular signal regulated kinase 1(ERK 1) enhances Smad2 transcriptional activity, which is negatively regulated by calmodulin. The regulation of Smad2 phosphorylation on threonine 8 by ERK 1 and calmodulin is critical for Smad2 mediated signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9933R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9933R-A750
Lokale Artikelnummer::
BOSSBS-9933R-A750
Beschreibung:
PTD015 is a 122 amino acid protein that belongs to the UPF0366 family. Existing as three alternatively spliced isoforms, the PTD015 gene is conserved in dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 11q14.1. With approximately 135 million base pairs and 1400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations. Wilms' tumours, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. The PTD015 gene product has been provisionally designated PTD015 pending further characterisation.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp), more appropriately called as stress response proteins (srp). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone GROEL730 reacts only with human and is useful in distinguishing human hsp60 from other mammalian and bacterial hsp60.
Artikel-Nr:
(USBI033250-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
033250-AP
Lokale Artikelnummer::
USBI033250-AP
Beschreibung:
Anti-CBX2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBI038178-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
038178-HRP
Lokale Artikelnummer::
USBI038178-HRP
Beschreibung:
Anti-MAPK4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-4032R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4032R-A647
Lokale Artikelnummer::
BOSSBS-4032R-A647
Beschreibung:
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010].
VE:
1 * 100 µl
Artikel-Nr:
(USBI031698-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031698-BIOTIN
Lokale Artikelnummer::
USBI031698-BIOTIN
Beschreibung:
Anti-AGL Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(AVIVARP45606_T100)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP45606_T100
Lokale Artikelnummer::
AVIVARP45606_T100
Beschreibung:
Anti-RORA Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-6325R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6325R-HRP
Lokale Artikelnummer::
BOSSBS-6325R-HRP
Beschreibung:
Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2004R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2004R-CY3
Lokale Artikelnummer::
BOSSBS-2004R-CY3
Beschreibung:
Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species jumping ability. Influenza A Virus [A/California/04/2009(H1N1)]
VE:
1 * 100 µl
Artikel-Nr:
(USBI031947-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031947-PE
Lokale Artikelnummer::
USBI031947-PE
Beschreibung:
Anti-AP3M1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(AVIVARP48808_P050)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP48808_P050
Lokale Artikelnummer::
AVIVARP48808_P050
Beschreibung:
Anti-POMGNT1 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-5128R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5128R-A488
Lokale Artikelnummer::
BOSSBS-5128R-A488
Beschreibung:
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5770R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5770R-A680
Lokale Artikelnummer::
BOSSBS-5770R-A680
Beschreibung:
FGF17 belongs to the heparin-binding growth factors family. It may be a signaling molecule in the induction and patterning of the embryonic brain and is preferentially expressed in the embryonic brain. There are two named isoforms.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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